SLC39A9

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Vemurafenib 6.6μM R08 exp434	-5.44
Caffeine 2600μM R08 exp463	-4.49
CoCl2 18μM R07 exp346	-4.33
ABT-702 5μM plus CoCl2 18μM R07 exp320	-4.19
Vemurafenib 6.6μM R02 exp89	-4.09
Fluvastatin 2.2μM R06 exp282	-3.77
Bafilomycin-A1 0.009μM R08 exp454	-3.6
ETC-159 50μM R08 exp480	-3.29
Cryptotanshinone 12μM R05 exp227	-3.17
Cerivastatin 0.15μM R05 exp226	-2.82
JQ1 0.8μM R08 exp435	-2.75
Clomiphene 4.4μM R02 exp68	-2.72
Hydroxychloroquine 30μM R08 exp490	-2.43
BS-181 20μM R08 exp461	-2.3
Artemisinin 50μM R08 exp450	-2.17
TRAIL 50ng/ml R00 exp36	-2.15
Hydroxyurea 100μM R07 exp329	-2.13
Azithromycin 100μM R08 exp452	-1.87
MK-1775 0.32μM R02 exp75	-1.75
Cannabidiol 20μM R08 exp466	-1.72
BH1 1μM R04 exp169	-1.71
Geldanamycin 0.015 to 0.025μM on day4 R07 exp316	2.02
Geldanamycin 0.015 to 0.05μM on day4 R07 exp317	2.03
VER-155008 3.9μM R06 exp301	2.03
Tunicamycin 0.04μM R07 exp418	2.52

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	1/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution

metal ion transmembrane transporter activity
zinc ion transport
transition metal ion transport
divalent metal ion transport
divalent inorganic cation transport
metal ion transport
cation transport
transmembrane transport
ion transport