USP37

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Global Fraction of Cell Lines Where Essential: 41/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	2/28
blood	1/28
bone	1/26
breast	4/33
central nervous system	1/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	1/16
kidney	4/21
liver	0/20
lung	3/75
lymphocyte	1/16
ovary	1/26
pancreas	1/24
peripheral nervous system	1/16
plasma cell	1/15
prostate	0/1
skin	0/24
soft tissue	1/9
thyroid	0/2
upper aerodigestive	1/22
urinary tract	2/29
uterus	1/5

Expression Distribution

protein K11-linked deubiquitination
protein K48-linked deubiquitination
thiol-dependent ubiquitinyl hydrolase activity
cysteine-type endopeptidase activity
thiol-dependent ubiquitin-specific protease activity
regulation of DNA replication
G1/S transition of mitotic cell cycle
cell cycle G1/S phase transition
mitotic cell cycle phase transition
cell cycle phase transition
protein deubiquitination
protein modification by small protein removal
protein kinase binding
cell division
ubiquitin-dependent protein catabolic process
modification-dependent protein catabolic process
modification-dependent macromolecule catabolic process
proteolysis involved in cellular protein catabolic process
mitotic cell cycle process
cellular protein catabolic process
protein catabolic process
mitotic cell cycle
cellular macromolecule catabolic process
protein modification by small protein conjugation or removal
cell cycle process
macromolecule catabolic process
organonitrogen compound catabolic process
proteolysis
cell cycle
organic substance catabolic process
cellular catabolic process