Pfam Domains GO Terms
| WW |
| PCIF1 WW |
| mRNA (2-O-methyladenosine-N6-)-methyltransferase activity |
| RNA polymerase II C-terminal domain binding |
| S-adenosyl-L-methionine binding |
| mRNA methylation |
| mRNA modification |
| intercellular bridge |
| RNA methylation |
| negative regulation of phosphatase activity |
| negative regulation of dephosphorylation |
| positive regulation of translation |
| positive regulation of cellular amide metabolic process |
| microtubule cytoskeleton |
| RNA modification |
| regulation of phosphatase activity |
| regulation of dephosphorylation |
| macromolecule methylation |
| methylation |
| regulation of translation |
| regulation of cellular amide metabolic process |
| negative regulation of hydrolase activity |
| posttranscriptional regulation of gene expression |
| negative regulation of phosphate metabolic process |
| negative regulation of phosphorus metabolic process |
| mRNA metabolic process |
| negative regulation of catalytic activity |
| negative regulation of molecular function |
| regulation of hydrolase activity |
| positive regulation of cellular protein metabolic process |
| RNA metabolic process |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution