TUBD1
Gene Information
- Official Symbol: TUBD1
- Official Name: tubulin delta 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 51174
- UniProt: Q9UJT1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Tubulin |
GO Terms
| positive regulation of smoothened signaling pathway |
| regulation of smoothened signaling pathway |
| structural constituent of cytoskeleton |
| centriole |
| cilium |
| microtubule |
| GTPase activity |
| GTP binding |
| microtubule cytoskeleton organization |
| microtubule-based process |
| mitotic cell cycle |
| cytoskeleton organization |
| cell projection organization |
| cell cycle |
| positive regulation of signal transduction |
| positive regulation of cell communication |
| positive regulation of signaling |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| C14orf80 | 0.788 |
| C16orf59 | 0.715 |
| TUBE1 | 0.715 |
| CASP2 | 0.613 |
| CEP120 | 0.596 |
| CEP44 | 0.579 |
| PIBF1 | 0.568 |
| C2CD3 | 0.568 |
| PIDD | 0.563 |
| CCDC41 | 0.553 |
| CRADD | 0.518 |
| ODF2 | 0.516 |
| BUB3 | 0.5 |
| CEP78 | 0.495 |
| KIAA0753 | 0.489 |
| FOPNL | 0.486 |
| ANKRD26 | 0.485 |
| ELP3 | 0.479 |
| OFD1 | 0.474 |
| SRP14 | 0.473 |
| DDX42 | 0.467 |
| GEMIN8 | 0.467 |
| NIN | 0.462 |
| TSEN54 | 0.456 |
| PMVK | 0.452 |
| N6AMT1 | 0.45 |
| RABGGTB | 0.448 |
| FGFR1OP | 0.446 |
| URM1 | 0.445 |
| WDR1 | 0.444 |
| TKT | 0.444 |
| PPCDC | 0.44 |
| GEMIN6 | 0.438 |
| PTAR1 | 0.434 |
| CENPA | 0.434 |
| THG1L | 0.431 |
| C15orf41 | 0.43 |
| DDX39A | 0.43 |
| ATIC | 0.429 |
| LSM10 | 0.421 |
| TEN1 | 0.42 |
| SCLT1 | 0.42 |
| SRP9 | 0.417 |
| TRMT61A | 0.417 |
| FKBPL | 0.416 |
| ATXN10 | 0.412 |
| PPP6C | 0.411 |
| ZCRB1 | 0.41 |
| SNAPC5 | 0.409 |
| HYLS1 | 0.408 |
| RPIA | 0.403 |
| CEP76 | 0.402 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 1657
- Expression level (log2 read counts): 4.43
Expression Distribution
TUBD1 Expression in NALM6 Cells: 4.43
