RALGAPB
Gene Information
- Official Symbol: RALGAPB
- Official Name: Ral GTPase activating protein non-catalytic subunit beta
- Aliases and Previous Symbols: N/A
- Entrez ID: 57148
- UniProt: Q86X10
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| activation of GTPase activity |
| GTPase activator activity |
| regulation of small GTPase mediated signal transduction |
| positive regulation of GTPase activity |
| regulation of GTPase activity |
| protein heterodimerization activity |
| positive regulation of hydrolase activity |
| regulation of hydrolase activity |
| positive regulation of catalytic activity |
| positive regulation of molecular function |
| regulation of intracellular signal transduction |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 5276
- Expression level (log2 read counts): 6.9
Expression Distribution
RALGAPB Expression in NALM6 Cells: 6.9
