SERF2

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
QNZ 0.01μM R05 exp241	-1.81
Arsenic trioxide 60μM R08 exp449	1.71
Lead acetate 2000μM R08 exp498 no dilution day6	1.73
BI-D1870 3.15μM R02 exp66	1.74
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	1.75
Olaparib 4μM R08 exp512	1.76
3-Bromopyruvate 7μM R04 exp175	1.83
Mitomycin-C 0.06μM R08 exp503	1.84
Nutlin-3A 1.6μM R06 exp294	1.84
PU-H71 1μM R08 exp515	1.87
6-Thio-2-deoxyguanosine 2μM R06 exp259	1.95
Sulforaphane 9μM R08 exp526 no dilution day6	1.99
CB-5083 0.4μM R08 exp468	2.19
RO-3307 4.7μM R02 exp80	2.19
Bortezomib 0.005μM R00 exp6	2.28
Thimerosal 0.85μM R08 exp529	2.32
Hippuristanol 0.12μM R08 exp489 no dilution day6	2.33
GSK626616 14μM R08 exp485	2.34
Staurosporine 0.02μM R08 exp524	2.42
Bleomycin 5μM R08 exp459	2.44
Etoposide 1μM R00 exp19	2.44
5-Fluorouracil 20μM R00 exp2	2.64
Dorsomorphin 5μM R07 exp357	2.71
Doxorubicin 0.02μM R08 exp478	2.73
Actinomycin-D 0.001μM R00 exp3	2.75
Pimelic-diphenylamide-106 5μM R00 exp28	2.83
MS023 2μM R03 exp134	2.85
Etoposide 0.3μM R05 exp199	2.86
Benzoate 20000μM R08 exp456	2.95
MS023 7μM R03 exp135	4.5

Global Fraction of Cell Lines Where Essential: 5/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	1/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	1/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	1/29
uterus	0/5

Expression Distribution