1-Methyl-nicotinamide-chloride 1000μM R03 exp113
Mechanism of Action
Nicotinamde metabolite, generated by nicotinamide N-methyltransferase (NNMT)
- Class / Subclass 1: Metabolism / Metabolite
Technical Notes
Compound References
- PubChem Name: 3-Carbamyl-1-methylpyridinium chloride
- Synonyms: N/A
- CAS #: 1005-24-9
- PubChem CID: 70495
- IUPAC: 1-methylpyridin-1-ium-3-carboxamide;chloride
- INCHI Name: InChI=1S/C7H8N2O.ClH/c1-9-4-2-3-6(5-9)7(8)10;/h2-5H,1H3,(H-,8,10);1H
- INCHI Key: BWVDQVQUNNBTLK-UHFFFAOYSA-N
- Molecular Weight: 172.61
- Canonical SMILES: C[N+]1=CC=CC(=C1)C(=O)N.[Cl-]
- Isomeric SMILES: N/A
- Molecular Formula: C7H9ClN2O
Compound Supplier
- Supplier Name: Santa Cruz Biotechnology
- Catalog #: N-3376
- Lot #: J2512
Compound Characterization
- HRMS (ESI-TOF) m/z: (M)+ Calcd for C7 H9 N2 O 137.07149; found 137.07026
Dose Response Curve
- Platform ID: 1-METH-NICOTINAMIDE
- Min: -8.6656; Max: 9.4829
| IC | Concentration (µM) |
|---|---|
| IC10 | N/A |
| IC20 | N/A |
| IC30 | N/A |
| IC40 | N/A |
| IC50 | N/A |
| IC60 | N/A |
| IC70 | N/A |
| IC80 | N/A |
| IC90 | N/A |
Screen Summary
- Round: 03
- Dose: 1000µM
- Days of incubation: 8
- Doublings: 7.8
- Numbers of reads: 10512009
Screen Results
| Sensitive/Resistant hits (FDR<0.05) | CRANKS | Score Plot | Top 30 Genes | Screen Similarity | Top 30 Sensitive GO terms | Top 30 Resistant GO terms |
|---|---|---|---|---|---|---|
| 0/0 | Scores |
1-Methyl-nicotinamide-chloride 1000μM R03 exp113
