Arsenate 40μM R06 exp264

Heavy metal toxin, environmental contaminant

PubChem Name: Sodium arsenate heptahydrate
Synonyms: N/A
CAS #: 10048-95-0
PubChem CID: 61460
IUPAC: disodium;hydrogen arsorate;heptahydrate
INCHI Name: InChI=1S/AsH3O4.2Na.7H2O/c2-1(3,4)5;;;;;;;;;/h(H3,2,3,4,5);;;7*1H2/q;2*+1;;;;;;;/p-2
INCHI Key: KOLXPEJIBITWIQ-UHFFFAOYSA-L
Molecular Weight: 312.01
Canonical SMILES: O.O.O.O.O.O.O.O[As](=O)([O-])[O-].[Na+].[Na+]
Isomeric SMILES: N/A
Molecular Formula: Na2HAsO4. 7H2O

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
26/153	Scores	View	View	View	View	View

Screen	Correlation	Plot
Thimerosal 0.85μM R08 exp529	0.086	View
Hippuristanol 0.12μM R08 exp488	0.08	View
Hippuristanol 0.12μM R08 exp489 no dilution day6	0.07	View
MLN-4924 0.2μM R00 exp21	0.066	View
Sulforaphane 9μM R08 exp525	0.064	View
GSK626616 14μM R08 exp485	0.063	View
Sulforaphane 9μM R08 exp526 no dilution day6	0.058	View
VER-155008 3.9μM R06 exp301	0.057	View
UM0125461 0.74μM R02 exp84	0.057	View
Milciclib 2μM R08 exp502	0.054	View
Trimetrexate 0.03μM R08 exp535	0.053	View
MS023 2μM R03 exp134	0.052	View
CB-5083 0.4μM R08 exp468	0.052	View
LLY-283 2.6μM R06 exp290	0.051	View
Nutlin-3A 1.6μM R06 exp294	0.051	View
AICAR 240μM R03 exp116	0.053	View
AICAR 240μM R05 exp211	0.052	View

GO Term	Fold Change	Genes
adenosine 5-(hexahydrogen pentaphosphate) catabolic process	381.03	NUDT11,NUDT10
diphosphoinositol-polyphosphate diphosphatase activity	381.03	NUDT11,NUDT10
diadenosine hexaphosphate metabolic process	381.03	NUDT11,NUDT10
diadenosine hexaphosphate catabolic process	285.78	NUDT11,NUDT10
diadenosine polyphosphate catabolic process	285.78	NUDT11,NUDT10
response to human chorionic gonadotropin	285.78	GCLM,GCLC
response to L-phenylalanine derivative	228.62	GCLM,GCLC
inositol phosphate metabolic process	61.24	NUDT11,PPIP5K2,NUDT10
mitotic cell cycle process	7.72	NSFL1C,TUBG1,RTF2,LCMT1,HDAC3,WAPL,CUL1

GO Term	Fold Change	Genes
inositol 5-diphosphate pentakisphosphate 5-kinase activity	552.50	IP6K2,IP6K1
inositol heptakisphosphate kinase activity	276.25	IP6K2,IP6K1
cAMP-dependent protein kinase activity	221.00	PRKAA1,PRKAG1
inositol phosphate biosynthetic process	138.12	IPPK,IP6K2,IPMK
inositol phosphate metabolic process	78.93	IPPK,IP6K2,IP6K1,IPMK
polyol biosynthetic process	50.23	IPPK,IP6K2,IP6K1,IPMK
alcohol biosynthetic process	30.69	IPPK,PRKAA1,IP6K2,IP6K1,IPMK
polyol metabolic process	24.56	IPPK,IP6K2,IP6K1,IPMK
protein kinase complex	19.05	PRKAA1,STRADA,PRKAG1,PRKAB1,STK11
organic hydroxy compound biosynthetic process	16.54	IPPK,PRKAA1,IP6K2,IP6K1,IPMK
small molecule biosynthetic process	9.87	IPPK,PRKAA1,IP6K2,PRKAG1,IP6K1,IPMK,PRKAB1,GPI
phosphotransferase activity, alcohol group as acceptor	7.34	IPPK,PRKAA1,IP6K2,STRADA,PRKAG1,IP6K1,IPMK,PRKAB1,STK11
phosphorylation	6.89	IPPK,PRKAA1,IP6K2,STRADA,PRKAG1,IP6K1,IPMK,PRKAB1,STK11
kinase activity	6.81	IPPK,PRKAA1,IP6K2,STRADA,PRKAG1,IP6K1,IPMK,PRKAB1,STK11
transferase activity, transferring phosphorus-containing groups	5.59	IPPK,PRKAA1,IP6K2,STRADA,PRKAG1,IP6K1,IPMK,PRKAB1,STK11