ISCA2

Gene Information
  • Official Symbol: ISCA2
  • Official Name: iron-sulfur cluster assembly 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 122961
  • UniProt: Q86U28
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is an A-type iron-sulfur cluster (ISC) protein found in mitochondria. The encoded protein appears to be involved in the maturation of mitochondrial iron-sulfur proteins. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012].
  • UniProt Summary: Involved in the maturation of mitochondrial 4Fe-4S proteins functioning late in the iron-sulfur cluster assembly pathway. May be involved in the binding of an intermediate of Fe/S cluster assembly. {ECO:0000269|PubMed:22323289}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1587
  • Expression level (log2 read counts): 4.21

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1