MIPEP
Gene Information
- Official Symbol: MIPEP
- Official Name: mitochondrial intermediate peptidase
- Aliases and Previous Symbols: N/A
- Entrez ID: 4285
- UniProt: Q99797
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The product of this gene performs the final step in processing a specific class of nuclear-encoded proteins targeted to the mitochondrial matrix or inner membrane. This protein is primarily involved in the maturation of oxidative phosphorylation (OXPHOS)-related proteins. This gene may contribute to the functional effects of frataxin deficiency and the clinical manifestations of Friedreich ataxia. [provided by RefSeq, Jul 2008].
- UniProt Summary: Cleaves proteins, imported into the mitochondrion, to their mature size.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 760
- Expression level (log2 read counts): 4.31