FAM122A
Gene Information
- Official Symbol: FAM122A
- Official Name: family with sequence similarity 122A
- Aliases and Previous Symbols: N/A
- Entrez ID: 116224
- UniProt: Q96E09
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: N/A
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| protein serine/threonine phosphatase inhibitor activity |
| negative regulation of phosphoprotein phosphatase activity |
| negative regulation of protein dephosphorylation |
| positive regulation of proteasomal ubiquitin-dependent protein catabolic process |
| positive regulation of ubiquitin-dependent protein catabolic process |
| positive regulation of proteasomal protein catabolic process |
| negative regulation of phosphatase activity |
| negative regulation of dephosphorylation |
| regulation of phosphoprotein phosphatase activity |
| positive regulation of proteolysis involved in cellular protein catabolic process |
| regulation of proteasomal ubiquitin-dependent protein catabolic process |
| regulation of protein dephosphorylation |
| positive regulation of cellular protein catabolic process |
| regulation of ubiquitin-dependent protein catabolic process |
| positive regulation of cell growth |
| regulation of phosphatase activity |
| regulation of proteasomal protein catabolic process |
| regulation of dephosphorylation |
| positive regulation of protein catabolic process |
| regulation of proteolysis involved in cellular protein catabolic process |
| regulation of cellular protein catabolic process |
| positive regulation of growth |
| positive regulation of proteolysis |
| positive regulation of cellular catabolic process |
| regulation of protein catabolic process |
| regulation of cell growth |
| positive regulation of catabolic process |
| negative regulation of hydrolase activity |
| negative regulation of phosphate metabolic process |
| negative regulation of phosphorus metabolic process |
| negative regulation of protein modification process |
| regulation of growth |
| regulation of proteolysis |
| negative regulation of catalytic activity |
| regulation of cellular catabolic process |
| regulation of catabolic process |
| negative regulation of cellular protein metabolic process |
| negative regulation of protein metabolic process |
| negative regulation of molecular function |
| regulation of hydrolase activity |
| positive regulation of cellular protein metabolic process |
| positive regulation of protein metabolic process |
| regulation of phosphate metabolic process |
| regulation of phosphorus metabolic process |
| regulation of protein modification process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 8/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 1/21 |
| liver | 1/20 |
| lung | 1/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 2/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 2/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 16677
- Expression level (log2 read counts): 4.52
Expression Distribution
FAM122A Expression in NALM6 Cells: 4.52
