METTL1
Gene Information
- Official Symbol: METTL1
- Official Name: methyltransferase like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 4234
- UniProt: Q9UBP6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene is similar in sequence to the S. cerevisiae YDL201w gene. The gene product contains a conserved S-adenosylmethionine-binding motif and is inactivated by phosphorylation. Alternative splice variants encoding different protein isoforms have been described for this gene. A pseudogene has been identified on chromosome X. [provided by RefSeq, Jul 2008].
- UniProt Summary: Catalyzes the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. {ECO:0000255|HAMAP-Rule:MF_03055, ECO:0000269|PubMed:12403464}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 472
- Expression level (log2 read counts): 4.17
METTL1 Expression in NALM6 Cells: 4.17
