SLC35B1

Gene Information

Official Symbol: SLC35B1
Official Name: solute carrier family 35 member B1
Aliases and Previous Symbols: N/A
Entrez ID: 10237
UniProt: P78383
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Probable sugar transporter. {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
SNS-032 25μM R07 exp401	1.78
Etoposide 0.3μM R05 exp199	1.79
Etoposide 1μM R00 exp19	1.81
DABN 20μM R00 exp17	1.84
MLN-4924 2μM R00 exp22	1.93
DABN racemic mixture R03 exp93	2.03
THZ1 0.06μM R08 exp531	2.2
Rotenone 20μM R00 exp34	2.39
SNS-032 15μM R08 exp443	2.46

Gene	Correlation
HARS	0.568
HSPD1	0.559
RNMT	0.527
DPAGT1	0.519
TTI2	0.516
SPCS3	0.513
AARS	0.508
DNAJC3	0.496
GMPPB	0.496
MED16	0.492
NARS	0.489
CCT7	0.489
GTF3C2	0.481
MARS	0.47
RPN1	0.47
TRIAP1	0.465
RPTOR	0.464
CSNK2B	0.462
SPCS2	0.462
EIF4E	0.457
GFPT1	0.456
CCDC101	0.454
ALG1	0.448
DAD1	0.447
CBFB	0.444
SMARCD1	0.444
MEAF6	0.443
BCL7A	0.439
RTCB	0.438
SRP72	0.437
TELO2	0.436
DHDDS	0.435
DERL2	0.435
UAP1	0.435
ALG5	0.435
MED23	0.435
MANF	0.433
ATP5O	0.432
GNB1L	0.431
ALG13	0.429
ATP5J	0.428
IRF2BP2	0.428
CARS	0.426
ALG2	0.425
TTI1	0.423
PELO	0.422
MLLT1	0.422
PMM2	0.42
THG1L	0.419
GTF3C3	0.418
GTF3C6	0.414
VRK1	0.412
BAP1	0.409
WARS	0.409
PPP2R3C	0.409
ATP5B	0.407
POLR3H	0.407
UBE2G2	0.407
ENY2	0.407
MAD2L1	0.406
DHPS	0.406
MTOR	0.405
ALG14	0.404
POLR3B	0.403
YARS	0.402

Global Fraction of Cell Lines Where Essential: 87/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	1/28
blood	2/28
bone	4/26
breast	2/33
central nervous system	7/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	4/16
kidney	5/21
liver	5/20
lung	8/75
lymphocyte	0/16
ovary	2/26
pancreas	1/24
peripheral nervous system	0/16
plasma cell	3/15
prostate	1/1
skin	2/24
soft tissue	2/9
thyroid	0/2
upper aerodigestive	5/22
urinary tract	3/29
uterus	1/5

Essentiality in NALM6

Essentiality Rank: 294
Expression level (log2 read counts): 6.49

Expression Distribution