Nifuroxazide 5μM R03 exp102

Nitrofuran antibiotic

PubChem Name: Nifuroxazide
Synonyms: N/A
CAS #: 965-52-6
PubChem CID: 5337997
IUPAC: 4-hydroxy-N-[(E)-(5-nitrofuran-2-yl)methylideneamino]benzamide
INCHI Name: InChI=1S/C12H9N3O5/c16-9-3-1-8(2-4-9)12(17)14-13-7-10-5-6-11(20-10)15(18)19/h1-7,16H,(H,14,17)/b13-7+
INCHI Key: YCWSUKQGVSGXJO-NTUHNPAUSA-N
Molecular Weight: 275.22
Canonical SMILES: C1=CC(=CC=C1C(=O)NN=CC2=CC=C(O2)[N+](=O)[O-])O
Isomeric SMILES: C1=CC(=CC=C1C(=O)N/N=C/C2=CC=C(O2)[N+](=O)[O-])O
Molecular Formula: C12H9N3O5

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
14/49	Scores	View	View	View	View	View

Screen	Correlation	Plot
THZ531 0.225μM R08 exp444	0.087	View
Trimetrexate 0.03μM R08 exp535	0.084	View
THZ531 0.11 to 0.175μM on day4 R07 exp413	0.08	View
Sulforaphane 9μM R08 exp525	0.074	View
Sulforaphane 9μM R08 exp526 no dilution day6	0.064	View
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	0.06	View
UM0131023 0.05μM R05 exp248	0.057	View
Rotenone 0.07μM R08 exp431	0.054	View
THZ531 0.11 to 0.125μM on day4 R07 exp410	0.052	View
MLN-4924 0.2μM R00 exp21	0.105	View
Citral 50μM R06 exp274	0.097	View
Ethanol 0.01 R05 exp234	0.077	View
MS023 2μM R03 exp134	0.072	View
ML-792 0.2μM R08 exp505	0.056	View
Mubritinib 0.2μM R01 exp48	0.056	View
Hippuristanol 0.12μM R08 exp488	0.056	View
Hippuristanol 0.12μM R08 exp489 no dilution day6	0.053	View
Citral 75μM R06 exp275	0.053	View

GO Term	Fold Change	Genes
pyruvate dehydrogenase (NAD+) activity	442.11	PDHA1,PDHB,DLAT,PDHX
B cell receptor complex	414.48	CD79A,CD79B,SYK
acetyl-CoA biosynthetic process from pyruvate	368.42	PDHB,DLAT,MPC2,PDHX
pyruvate dehydrogenase activity	331.58	PDHA1,DLAT,PDHX
pyruvate dehydrogenase [NAD(P)+] activity	331.58	PDHA1,PDHB,PDHX
immunoglobulin complex	221.05	CD79A,CD79B,SYK,IGLL1
acetyl-CoA biosynthetic process	212.55	PDHA1,PDHB,DLAT,MPC2,PDHX
acetyl-CoA metabolic process	98.68	PDHA1,PDHB,DLAT,MPC2,PDHX
thioester biosynthetic process	82.90	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
acyl-CoA biosynthetic process	82.90	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
ribonucleoside bisphosphate biosynthetic process	65.02	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
purine nucleoside bisphosphate biosynthetic process	65.02	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
nucleoside bisphosphate biosynthetic process	65.02	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
acyl-CoA metabolic process	38.11	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
thioester metabolic process	38.11	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
ribonucleoside bisphosphate metabolic process	28.83	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
purine nucleoside bisphosphate metabolic process	28.83	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
nucleoside bisphosphate metabolic process	28.83	PDHA1,PDHB,DLAT,MPC2,PDHX,ACSL4
ribose phosphate biosynthetic process	19.64	PDHA1,PDHB,DLAT,MPC2,PRPS1,PDHX,ACSL4