Pfam Domains GO Terms
| Golgi cis cisterna |
| cis-Golgi network |
| Golgi cisterna membrane |
| spindle assembly |
| Golgi organization |
| spindle organization |
| endomembrane system organization |
| microtubule cytoskeleton organization |
| microtubule-based process |
| organelle assembly |
| Golgi apparatus |
| cell cycle process |
| cytoskeleton organization |
| cell cycle |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Screen | Score |
|---|---|
| Tanespimycin 14μM R08 exp527 | -1.81 |
| Gene | Correlation |
|---|---|
| TCEB3C | 0.52 |
| VASN | 0.516 |
| ORC6 | 0.515 |
| COPE | 0.508 |
| ORC1 | 0.498 |
| TCEB3CL | 0.497 |
| TCEB3CL2 | 0.495 |
| CCDC64B | 0.49 |
| CHD4 | 0.489 |
| TBC1D3 | 0.489 |
| TICRR | 0.487 |
| TBC1D3G | 0.487 |
| C1QTNF9B | 0.486 |
| KCTD17 | 0.476 |
| TBC1D3H | 0.474 |
| TFIP11 | 0.474 |
| SLC4A1 | 0.473 |
| PSMD3 | 0.473 |
| AKIRIN2 | 0.47 |
| TBC1D3C | 0.47 |
| PSMA6 | 0.47 |
| RAD51 | 0.469 |
| POLE | 0.469 |
| TP53TG3B | 0.468 |
| TP53TG3 | 0.467 |
| TP53TG3C | 0.467 |
| TWISTNB | 0.467 |
| SUPT6H | 0.463 |
| CMYA5 | 0.462 |
| AAMP | 0.46 |
| RPL9 | 0.459 |
| SAP30BP | 0.457 |
| TBC1D3F | 0.457 |
| SYT9 | 0.45 |
| NUPL1 | 0.448 |
| DNTTIP2 | 0.448 |
| C14orf93 | 0.446 |
| DTL | 0.446 |
| CBWD6 | 0.446 |
| CBWD3 | 0.444 |
| PSMC1 | 0.443 |
| CCNA2 | 0.434 |
| RPS19BP1 | 0.433 |
| SF3A3 | 0.432 |
| DOCK6 | 0.432 |
| SEC13 | 0.432 |
| RRN3 | 0.43 |
| GOLGA8O | 0.429 |
| OGFR | 0.429 |
| CDC45 | 0.427 |
| RPS2 | 0.426 |
| OSBP | 0.423 |
| LRR1 | 0.423 |
| RIOK2 | 0.422 |
| SPRR2B | 0.419 |
| PSMB4 | 0.419 |
| RPS3A | 0.418 |
| MYLK3 | 0.417 |
| RPL7L1 | 0.416 |
| IK | 0.415 |
| CDC6 | 0.415 |
| PSMB2 | 0.415 |
| SF3A2 | 0.414 |
| ELMOD3 | 0.414 |
| CHAF1A | 0.413 |
| FBXW9 | 0.413 |
| CBWD5 | 0.412 |
| ACSF2 | 0.411 |
| EXOSC5 | 0.409 |
| SLC6A17 | 0.409 |
| NUP160 | 0.409 |
| MT1E | 0.409 |
| NPIPB5 | 0.409 |
| GOSR2 | 0.408 |
| ANKLE2 | 0.408 |
| GON4L | 0.408 |
| PSMD6 | 0.405 |
| IGFN1 | 0.405 |
| RPS12 | 0.405 |
| WDR87 | 0.405 |
| STIL | 0.405 |
| AQR | 0.404 |
| COPG1 | 0.404 |
| AATF | 0.404 |
| NUP205 | 0.403 |
| COPA | 0.403 |
| TM7SF2 | 0.403 |
| SLC5A5 | 0.402 |
| CLN6 | 0.402 |
| FAM160A1 | 0.401 |
| NAPA | 0.401 |
| ZNF830 | 0.4 |
| RAD21 | 0.4 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 1/28 |
| blood | 2/28 |
| bone | 0/26 |
| breast | 2/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 2/16 |
| kidney | 0/21 |
| liver | 1/20 |
| lung | 7/75 |
| lymphocyte | 2/16 |
| ovary | 2/26 |
| pancreas | 2/24 |
| peripheral nervous system | 2/16 |
| plasma cell | 2/15 |
| prostate | 1/1 |
| skin | 0/24 |
| soft tissue | 1/9 |
| thyroid | 0/2 |
| upper aerodigestive | 1/22 |
| urinary tract | 1/29 |
| uterus | 0/5 |
Expression Distribution