C19orf53

Entrez Summary: N/A
UniProt Summary: May have a potential role in hypercalcemia of malignancy. {ECO:0000250}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
iCRT14 30μM R08 exp492	-2.07
GSK-J4 1.5μM R08 exp441	-1.76
CCCP 0.1μM R00 exp10	1.72
Trichostatin-A 0.06μM R07 exp415	1.72
Talazoparib 0.006μM R06 exp299	1.73
GSK2606414 1μM R05 exp236	1.75
Zebularine 20μM R07 exp423	1.75
A-395N 10μM R05 exp219	1.78
VE-822 0.04μM R06 exp300	1.79
Chloramphenicol 2μM R00 exp12	1.8
GSK-LSD1 10μM R03 exp123	1.83
Methotrexate 0.01μM R08 exp501	1.84
Vemurafenib 6.6μM R08 exp434	1.87
Cholesterol 0.003 to 0.006 to 0.1μM on day2 then day6 R08 exp471	1.88
Dimethyloxaloylglycine 100μM R05 exp229	1.92
Nocodazole 0.02μM R00 exp23	1.94
Cycloheximide 0.02μM R00 exp14	1.97
KU-0063794 3.8μM R02 exp71	1.98
THZ531 0.11μM R07 exp409	1.98
LLY-284 2.6μM R06 exp291	2
Ethanol 0.01 R05 exp234	2.03
Chloramphenicol 20μM R00 exp13	2.04
Thioridazine 5μM R08 exp530	2.04
5-Fluorouracil 2μM R00 exp1	2.15
Resminostat 0.5μM R07 exp393	2.16
DABN 2μM R00 exp16	2.26
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	2.29
THZ531 0.11 to 0.175μM on day4 R07 exp413	2.64
Rapamycin 1μM R00 exp29	2.73
THZ531 0.225μM R08 exp444	3.56

Global Fraction of Cell Lines Where Essential: 175/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	10/28
blood	2/28
bone	6/26
breast	8/33
central nervous system	17/56
cervix	0/4
colorectal	2/17
esophagus	2/13
fibroblast	1/1
gastric	1/16
kidney	11/21
liver	4/20
lung	17/75
lymphocyte	2/16
ovary	9/26
pancreas	4/24
peripheral nervous system	4/16
plasma cell	1/15
prostate	0/1
skin	6/24
soft tissue	1/9
thyroid	1/2
upper aerodigestive	10/22
urinary tract	5/29
uterus	0/5

Expression Distribution