RPL38
Gene Information
- Official Symbol: RPL38
- Official Name: ribosomal protein L38
- Aliases and Previous Symbols: N/A
- Entrez ID: 6169
- UniProt: P63173
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ribosomal L38e |
GO Terms
| eukaryotic 80S initiation complex |
| 90S preribosome assembly |
| axial mesoderm development |
| middle ear morphogenesis |
| ribosomal small subunit assembly |
| ribosomal large subunit assembly |
| polysomal ribosome |
| ribosome assembly |
| cytosolic large ribosomal subunit |
| ribosomal small subunit biogenesis |
| ribosomal large subunit biogenesis |
| cytoplasmic translation |
| SRP-dependent cotranslational protein targeting to membrane |
| cotranslational protein targeting to membrane |
| protein targeting to ER |
| establishment of protein localization to endoplasmic reticulum |
| viral transcription |
| ear morphogenesis |
| nuclear-transcribed mRNA catabolic process, nonsense-mediated decay |
| mesoderm development |
| viral gene expression |
| protein localization to endoplasmic reticulum |
| translational initiation |
| sensory perception of sound |
| protein targeting to membrane |
| sensory perception of mechanical stimulus |
| structural constituent of ribosome |
| nuclear-transcribed mRNA catabolic process |
| mRNA catabolic process |
| ear development |
| ribonucleoprotein complex assembly |
| ribonucleoprotein complex subunit organization |
| RNA catabolic process |
| postsynaptic density |
| sensory organ morphogenesis |
| ossification |
| establishment of protein localization to membrane |
| embryonic organ morphogenesis |
| ribosome biogenesis |
| regulation of translation |
| protein targeting |
| nucleobase-containing compound catabolic process |
| translation |
| regulation of cellular amide metabolic process |
| peptide biosynthetic process |
| focal adhesion |
| establishment of protein localization to organelle |
| embryonic organ development |
| heterocycle catabolic process |
| cellular nitrogen compound catabolic process |
| aromatic compound catabolic process |
| ribonucleoprotein complex biogenesis |
| protein localization to membrane |
| organic cyclic compound catabolic process |
| skeletal system development |
| posttranscriptional regulation of gene expression |
| amide biosynthetic process |
| peptide metabolic process |
| sensory organ development |
| embryonic morphogenesis |
| mRNA metabolic process |
| viral process |
| protein localization to organelle |
| organelle assembly |
| symbiotic process |
| cellular amide metabolic process |
| interspecies interaction between organisms |
| cellular protein-containing complex assembly |
| cellular macromolecule catabolic process |
| animal organ morphogenesis |
| sensory perception |
| embryo development |
| intracellular protein transport |
| macromolecule catabolic process |
| nervous system process |
| RNA binding |
| organonitrogen compound biosynthetic process |
| protein transport |
| intracellular transport |
| peptide transport |
| protein-containing complex assembly |
| amide transport |
| cellular protein localization |
| cellular macromolecule localization |
| establishment of protein localization |
| cellular nitrogen compound biosynthetic process |
| RNA metabolic process |
| cellular macromolecule biosynthetic process |
| negative regulation of gene expression |
| tissue development |
| macromolecule biosynthetic process |
| organic substance catabolic process |
| cellular catabolic process |
| establishment of localization in cell |
| nitrogen compound transport |
| protein-containing complex subunit organization |
| system process |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| RPL34 | 0.494 |
| RPL35 | 0.481 |
| RBBP5 | 0.473 |
| CKAP5 | 0.467 |
| PSMB4 | 0.463 |
| NUP43 | 0.462 |
| CACTIN | 0.451 |
| PPIE | 0.444 |
| BRIX1 | 0.436 |
| RPS2 | 0.434 |
| CDC73 | 0.433 |
| ZFAND5 | 0.432 |
| TCEB3CL2 | 0.431 |
| CASC5 | 0.429 |
| TBC1D3C | 0.428 |
| RBM39 | 0.428 |
| RPS28 | 0.426 |
| PWP2 | 0.424 |
| SMG7 | 0.424 |
| C19orf53 | 0.422 |
| BOD1L1 | 0.421 |
| CEBPZ | 0.421 |
| PAF1 | 0.42 |
| MDM2 | 0.417 |
| PCF11 | 0.417 |
| RRP15 | 0.413 |
| INTS6 | 0.413 |
| RIOK2 | 0.411 |
| NARFL | 0.409 |
| WDR43 | 0.408 |
| RPS9 | 0.406 |
| PSMB1 | 0.405 |
| PSMD1 | 0.405 |
| CTR9 | 0.405 |
| STIL | 0.403 |
| PELP1 | 0.402 |
| HIST2H3A | 0.401 |
| RSL1D1 | 0.401 |
| LAD1 | 0.401 |
| RRP1 | 0.4 |
| HIST2H3C | 0.4 |
| S1PR4 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 490/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 1/1 |
| 909776.0 | 1/1 |
| bile duct | 18/28 |
| blood | 20/28 |
| bone | 13/26 |
| breast | 22/33 |
| central nervous system | 41/56 |
| cervix | 2/4 |
| colorectal | 12/17 |
| esophagus | 8/13 |
| fibroblast | 1/1 |
| gastric | 10/16 |
| kidney | 13/21 |
| liver | 13/20 |
| lung | 41/75 |
| lymphocyte | 8/16 |
| ovary | 18/26 |
| pancreas | 13/24 |
| peripheral nervous system | 8/16 |
| plasma cell | 11/15 |
| prostate | 1/1 |
| skin | 15/24 |
| soft tissue | 7/9 |
| thyroid | 2/2 |
| upper aerodigestive | 17/22 |
| urinary tract | 21/29 |
| uterus | 4/5 |
Essentiality in NALM6
- Essentiality Rank: 1061
- Expression level (log2 read counts): 7.64
Expression Distribution
RPL38 Expression in NALM6 Cells: 7.64
