C6orf136

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
GSK-J4 1μM R07 exp362	-3.89
2-Deoxy-D-glucose 800μM R05 exp214	-3.58
GSK-J4 1-1.25μM to day4 R07 exp363	-3.51
UM0131023 0.05μM R05 exp248	-2.67
IU1-C 25μM R04 exp183	-2.66
Artemisinin 50μM R08 exp450	-2.65
Menadione 5μM R06 exp292	-2.61
Citral 50μM R06 exp274	-2.55
A-196 10μM R03 exp114	-2.21
FK-506 5μM R07 exp358	-2.11
Talazoparib 0.006μM R06 exp299	-2.11
RS-1 10μM R08 exp519	-2.09
Vinorelbine 0.001μM R05 exp249	-1.99
GW501516 25μM R06 exp285	-1.94
SB202190 10μM R03 exp148	-1.92
Rotenone 20μM R00 exp34	-1.91
CB-839 10μM R05 exp224	-1.9
QNZ 0.01μM R05 exp241	-1.89
Taxol 0.002μM R01 exp54	-1.85
MS023 7μM R03 exp135	-1.84
ABT-702 0.1μM R06 exp260	-1.83
GSK-J4 1.5μM R08 exp441	-1.82
LY2090314 0.003μM R08 exp499	-1.82
Mubritinib 0.2μM R01 exp48	-1.8
NMS-873 0.07μM R07 exp380	-1.79
Lead acetate 2000μM R08 exp497	-1.76
Cryptotanshinone 12μM R05 exp227	-1.71
Bisphenol A 100μM R06 exp269	1.7
Pimelic-diphenylamide-106 5μM R00 exp28	1.76
Momordin-Ic 10μM R08 exp506	1.85
Salubrinal 20μM R07 exp399	1.94
All-trans-Retinoic-Acid 40μM R07 exp334	1.98
CCCP 1μM R00 exp11	2.02
Etoposide 0.3μM R05 exp199	2.48

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution