SLC25A51

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
2-Methoxyestradiol 0.55μM R07 exp310	1.7
MS023 7μM R03 exp135	1.7
RK-33 8μM R08 exp518	1.72
Selumetinib 20μM R02 exp81	1.73
Talazoparib 0.006μM R06 exp299	1.73
Dorsomorphin 5μM R07 exp357	1.76
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	1.77
Trientine 500μM R08 exp534	1.78
Taxol 0.004μM R03 exp103	1.81
Trichostatin-A 0.06μM R07 exp415	1.85
BI-D1870 3.15μM R02 exp66	1.88
Doxorubicin 0.02μM R08 exp478	1.89
Erlotinib 10μM R05 exp216	1.9
Deguelin 0.15μM R05 exp209	1.93
Artemisinin 50μM R08 exp450	1.94
Vinblastine 0.002μM R01 exp60	1.94
FK-506 30μM R07 exp359	2.08
LLY-283 2.6μM R06 exp290	2.14
Quercetin 20μM R08 exp517	2.21
Nutlin-3A 1.6μM R06 exp294	2.22
Epothilone-B 0.0015μM R05 exp231	2.29
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	2.46
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	2.47
Docetaxel 0.002μM R01 exp45	2.56
VER-155008 3.9μM R06 exp301	2.59
iCRT14 30μM R08 exp492	2.79
Arsenate 40μM R06 exp264	2.81
UMK57 1μM R01 exp59	3.1
HMS-I2 10μM R06 exp288	3.12
Amiloride 100μM R08 exp447	3.35
Phenformin 20μM R05 exp212	3.39
Chloramphenicol 20μM R00 exp13	3.92
Genistein 15μM R07 exp360	4.06
NMS-873 0.07μM R07 exp380	4.12
AICAR 240μM R03 exp116	4.19
Oligomycin-A 2μM R00 exp25	4.24
AICAR 240μM R05 exp211	4.28
Rotenone 0.07μM R08 exp431	4.34
QNZ 0.01μM R05 exp241	4.48
QNZ 0.01μM R08 exp439	4.79
Phenformin 20μM R03 exp143	4.98
Mubritinib 0.2μM R02 exp65	5.04
Mubritinib 0.2μM R01 exp48	6.22

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Expression Distribution