STARD7

Entrez Summary: N/A
UniProt Summary: May play a protective role in mucosal tissues by preventing exaggerated allergic responses. {ECO:0000250|UniProtKB:Q8R1R3}.

Pfam Domains GO Terms

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-3.29
Etoposide 10μM R00 exp20	-2.89
Artemisinin 50μM R08 exp450	-2.86
Cryptotanshinone 12μM R05 exp227	-2.49
∆-9-Tetrahydrocannabinol 30μM R08 exp445	-2.26
Deferoxamine 11μM R07 exp350	-1.96
Q15 2.7μM R02 exp79	-1.96
Centrinone 0.5μM R07 exp343	-1.95
Rotenone 20μM R00 exp34	-1.83
SNS-032 15μM R08 exp443	-1.8
Bortezomib 0.05μM R00 exp7	-1.77
Methotrexate 0.01μM R08 exp501	-1.77
Tenofovir 10μM R07 exp405	-1.74
THZ1 0.06μM R08 exp531	-1.72
NMS-873 0.07μM R07 exp380	1.7
A-366 10μM R03 exp115	1.71
QNZ 0.01μM R08 exp439	1.71
Benzoate 10000μM R08 exp455	1.76
ETC-159 50μM R08 exp480	1.81
Benzoate 20000μM R08 exp456	1.82
BI-6727 0.001μM R01 exp42	1.83
Ethanol 0.01 R05 exp234	1.83
QNZ 0.01μM R05 exp241	1.91
Bisphenol A 100μM R06 exp269	1.96
Chloramphenicol 2μM R00 exp12	1.99
UM0131023 0.05μM R05 exp248	2.05
Dimethyloxaloylglycine 100μM R05 exp229	2.19
RK-33 8μM R08 exp518	2.2
Calcium Ionophore 0.4μM R07 exp342	2.4
Vincristine 0.0005μM R04 exp190	2.54
Amiloride 100μM R08 exp447	2.68
Chloramphenicol 20μM R00 exp13	2.81
iCRT14 30μM R08 exp492	3.38
GSK-J4 1-1.25μM to day4 R07 exp363	3.53
UM0129480 7μM R02 exp85	3.6
Hypoxia 5%O2 R04 exp191	4.2
Doxycycline 10μM R00 exp18	4.92
GSK-J4 1.5μM R08 exp441	5.41
FK-506 30μM R07 exp359	6.06
Oligomycin-A 2μM R00 exp25	8.3

Global Fraction of Cell Lines Where Essential: 24/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	2/28
blood	0/28
bone	0/26
breast	2/33
central nervous system	1/56
cervix	0/4
colorectal	1/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	1/20
lung	3/75
lymphocyte	0/16
ovary	1/26
pancreas	0/24
peripheral nervous system	1/16
plasma cell	0/15
prostate	0/1
skin	2/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	3/22
urinary tract	1/29
uterus	0/5

Expression Distribution

phospholipid transporter activity
phosphatidylcholine biosynthetic process
phosphatidylcholine metabolic process
phospholipid transport
organophosphate ester transport
lipid binding
mitochondrial outer membrane
ammonium ion metabolic process
glycerophospholipid biosynthetic process
glycerolipid biosynthetic process
phospholipid biosynthetic process
lipid transport
glycerophospholipid metabolic process
lipid localization
phospholipid metabolic process
glycerolipid metabolic process
organic anion transport
organophosphate biosynthetic process
lipid biosynthetic process
anion transport
organophosphate metabolic process
cellular lipid metabolic process
lipid metabolic process
ion transport
organonitrogen compound biosynthetic process