ATF7IP
Gene Information
- Official Symbol: ATF7IP
- Official Name: activating transcription factor 7 interacting protein
- Aliases and Previous Symbols: N/A
- Entrez ID: 55729
- UniProt: Q6VMQ6
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| positive regulation of methylation-dependent chromatin silencing |
| regulation of methylation-dependent chromatin silencing |
| regulation of RNA polymerase II transcriptional preinitiation complex assembly |
| positive regulation of chromatin silencing |
| regulation of transcription initiation from RNA polymerase II promoter |
| regulation of DNA-templated transcription, initiation |
| regulation of chromatin silencing |
| DNA alkylation |
| DNA methylation |
| DNA methylation or demethylation |
| DNA modification |
| positive regulation of chromatin organization |
| regulation of gene silencing |
| positive regulation of chromosome organization |
| protein stabilization |
| regulation of chromatin organization |
| transcription factor complex |
| ATPase activity |
| transcription corepressor activity |
| macromolecule methylation |
| nuclear body |
| regulation of protein stability |
| methylation |
| regulation of chromosome organization |
| regulation of protein complex assembly |
| positive regulation of organelle organization |
| viral process |
| DNA metabolic process |
| symbiotic process |
| interspecies interaction between organisms |
| negative regulation of transcription by RNA polymerase II |
| regulation of cellular component biogenesis |
| negative regulation of transcription, DNA-templated |
| positive regulation of cellular component organization |
| negative regulation of nucleic acid-templated transcription |
| negative regulation of RNA biosynthetic process |
| regulation of organelle organization |
| negative regulation of RNA metabolic process |
| negative regulation of cellular macromolecule biosynthetic process |
| negative regulation of nucleobase-containing compound metabolic process |
| negative regulation of macromolecule biosynthetic process |
| negative regulation of cellular biosynthetic process |
| positive regulation of transcription, DNA-templated |
| negative regulation of biosynthetic process |
| positive regulation of nucleic acid-templated transcription |
| positive regulation of RNA biosynthetic process |
| negative regulation of gene expression |
| positive regulation of RNA metabolic process |
| positive regulation of nucleobase-containing compound metabolic process |
| positive regulation of macromolecule biosynthetic process |
| positive regulation of cellular biosynthetic process |
| positive regulation of gene expression |
| positive regulation of biosynthetic process |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| CBX3 | 0.596 |
| SETDB1 | 0.538 |
| MLLT1 | 0.512 |
| ID3 | 0.51 |
| THOC6 | 0.506 |
| MED23 | 0.503 |
| DHX29 | 0.486 |
| DOHH | 0.47 |
| CCDC101 | 0.468 |
| GNB1L | 0.463 |
| MAPK14 | 0.463 |
| BAP1 | 0.459 |
| NSD1 | 0.457 |
| ZNF592 | 0.451 |
| MAML1 | 0.446 |
| TRIP12 | 0.445 |
| TRIM28 | 0.443 |
| RPTOR | 0.443 |
| TTI2 | 0.442 |
| CBFB | 0.435 |
| ARIH1 | 0.433 |
| TAF5L | 0.432 |
| TADA1 | 0.425 |
| ARL14EP | 0.424 |
| RNMT | 0.423 |
| BRPF1 | 0.421 |
| DDX5 | 0.419 |
| AARS | 0.418 |
| TAF6L | 0.417 |
| SSBP2 | 0.417 |
| TTI1 | 0.415 |
| TMEM41B | 0.415 |
| HHEX | 0.414 |
| OTUD5 | 0.413 |
| IRF2BP2 | 0.413 |
| FBXO11 | 0.412 |
| GTF3C3 | 0.412 |
| LAMTOR4 | 0.411 |
| TCEB3 | 0.41 |
| DPAGT1 | 0.409 |
| DCAF5 | 0.406 |
| XPOT | 0.406 |
| MED16 | 0.405 |
| ZNF445 | 0.402 |
| SOX7 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/726
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/25 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/15 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/14 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/7 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6785
- Expression level (log2 read counts): 6.92
Expression Distribution
ATF7IP Expression in NALM6 Cells: 6.92
