C15orf41

Gene Information

Official Symbol: C15orf41
Official Name: chromosome 15 open reading frame 41
Aliases and Previous Symbols: N/A
Entrez ID: 84529
UniProt: Q9Y2V0
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: This gene encodes a protein with two predicted helix-turn-helix domains. Mutations in this gene were found in families with congenital dyserythropoietic anemia type Ib. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2014].
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Nifurtimox 1μM R03 exp141	-2.03
A-395N 10μM R05 exp219	-1.99
NFN1 1μM R03 exp100	-1.77
Senexin-A 25μM R07 exp400	1.73
BVD-523 15μM R02 exp67	2.13
Dorsomorphin 5μM R07 exp357	2.25
Palbociclib 1μM R07 exp382	2.38
2-Deoxy-D-glucose 800μM R05 exp214	2.54
Cannabidiol 20μM R08 exp466	2.7

Gene	Correlation
GEMIN8	0.622
GEMIN6	0.556
THG1L	0.536
HARS	0.522
TEN1	0.519
PTAR1	0.517
RPIA	0.512
RFT1	0.508
PPCS	0.507
RABGGTB	0.506
ATIC	0.505
CTC1	0.493
URM1	0.49
RTCB	0.489
ELP3	0.488
TBCB	0.487
DR1	0.484
TPRKB	0.478
PGM3	0.476
GEMIN7	0.475
SRP14	0.472
RAD50	0.468
PPP6C	0.468
PPP4C	0.467
VEZT	0.467
ATXN10	0.467
FH	0.466
MSTO1	0.465
ADSL	0.465
RPP21	0.462
LSM10	0.461
TPK1	0.461
ALG1	0.458
SLC25A19	0.457
TTC4	0.456
TUBE1	0.45
TSEN54	0.45
ZRSR2	0.447
DOLK	0.446
RFK	0.446
DHRSX	0.446
PMVK	0.445
DNLZ	0.443
ZCRB1	0.443
SNAPC5	0.442
UAP1	0.441
PDCD5	0.439
PPCDC	0.438
GEMIN4	0.438
SRD5A3	0.438
MOCS3	0.437
GMPPB	0.437
TUBD1	0.43
UHRF1	0.429
N6AMT1	0.428
DDX55	0.42
AASDHPPT	0.417
DDX39A	0.417
TAMM41	0.417
DDX1	0.416
TRMT6	0.414
DOHH	0.414
CXorf56	0.413
MRPS14	0.412
FKBPL	0.412
PPA1	0.41
DPAGT1	0.407
SSB	0.406
TSEN34	0.405
RPTOR	0.404
TRMT61A	0.404
GCLC	0.404
NBN	0.403
FEN1	0.403
ZNHIT1	0.402

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	1/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 773
Expression level (log2 read counts): 3.58

Expression Distribution