PPFIA4

Gene Information

Official Symbol: PPFIA4
Official Name: PTPRF interacting protein alpha 4
Aliases and Previous Symbols: N/A
Entrez ID: 8497
UniProt: O75335
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: May regulate the disassembly of focal adhesions. May localize receptor-like tyrosine phosphatases type 2A at specific sites on the plasma membrane, possibly regulating their interaction with the extracellular environment and their association with substrates (By similarity). {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
TBC1D3H	0.553
TBC1D3F	0.552
TBC1D3G	0.55
TFIP11	0.536
NUPL1	0.503
TBC1D3	0.498
RPS28	0.497
TCEB3CL2	0.495
RPS12	0.489
TCEB3C	0.476
TBC1D3C	0.472
IK	0.471
AKIRIN2	0.466
HIVEP3	0.461
TCEB3CL	0.46
RPL35	0.458
ORC6	0.455
RPS2	0.45
PSMB2	0.447
NUP85	0.446
AAMP	0.444
ZNF830	0.444
CKAP5	0.444
DNTTIP2	0.443
TBC1D3K	0.442
TBC1D3E	0.442
TBC1D3I	0.442
TBC1D3L	0.441
NUP133	0.441
CDC73	0.437
PSMC6	0.437
RPS9	0.437
VASN	0.436
DDTL	0.435
POLA2	0.432
CDCA3	0.431
XYLT2	0.43
ANKLE2	0.43
PSMA6	0.429
DOCK6	0.429
CENPP	0.428
KRT78	0.428
TICRR	0.428
SNRPA1	0.424
C1QTNF9B	0.423
HAP1	0.423
CCDC64B	0.422
S1PR4	0.422
C14orf93	0.42
POLE	0.42
NDC1	0.42
CHD4	0.419
NARFL	0.418
CBWD5	0.417
FCN2	0.415
CBWD3	0.415
C2orf27B	0.413
ARHGEF35	0.413
SF3A1	0.41
NDC80	0.409
COPE	0.409
NOP16	0.408
NAALADL1	0.407
PSMD1	0.406
MT1E	0.406
CHAF1A	0.405
LRR1	0.405
RAD21	0.405
LAD1	0.404
CDC6	0.403
SUPT5H	0.403
SYT9	0.403
SCAF1	0.402
KCTD17	0.402
TTYH1	0.401
TWISTNB	0.401

Essentiality in NALM6

Essentiality Rank: 2196
Expression level (log2 read counts): 7.11

Expression Distribution