EBNA1BP2 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: EBNA1BP2
Official Name: EBNA1 binding protein 2
Aliases and Previous Symbols: N/A
Entrez ID: 10969
UniProt: Q99848
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: Required for the processing of the 27S pre-rRNA. {ECO:0000250}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
ONC212 0.15μM R08 exp513	-2.04
THZ1 0.06μM R08 exp531	-1.85
Tunicamycin 0.04 to 0.075μM on day4 R07 exp419	1.74
Zebularine 20μM R07 exp423	1.8
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	1.83
Golgicide-A 4μM R03 exp122	1.92
Thalidomide 20μM R07 exp406	1.92
BRD2 inhibitor II 20μM R07 exp341	2.07

Gene	Correlation
RRM1	0.562
RPL35	0.527
C1QTNF9B	0.495
GOLGA6L3	0.492
TCEB3CL2	0.481
TBC1D3H	0.478
RRP7A	0.476
TCEB3C	0.474
CHD4	0.468
C14orf93	0.468
KCTD17	0.467
TBC1D3	0.466
RRN3	0.465
TBC1D3C	0.462
MPHOSPH10	0.46
GOLGA8R	0.46
DISP2	0.458
UTP3	0.456
NOL10	0.452
POLR2J3	0.452
PSMD2	0.451
RPS19	0.451
RPLP0	0.45
RNPC3	0.448
POLE	0.448
RPS5	0.448
RPS12	0.448
EXOSC9	0.447
TCEB3CL	0.446
TBC1D3G	0.445
TBC1D3F	0.444
TBC1D3K	0.441
TBC1D3E	0.441
TBC1D3L	0.441
TBC1D3I	0.441
PSMB4	0.44
RBBP5	0.44
PSMB2	0.439
NOL7	0.439
UTP20	0.436
DTL	0.435
RPL6	0.434
PAN3	0.433
PDE4DIP	0.432
HIST2H3A	0.431
SLC6A17	0.431
RPS3A	0.43
HIST2H3C	0.43
CHCHD3	0.43
ZFAND5	0.428
SDE2	0.428
PSMB1	0.428
PPAN	0.428
EXOSC1	0.427
CDH24	0.427
RPA2	0.422
COL2A1	0.421
DDTL	0.42
VPS28	0.42
NCAPG	0.42
PSMC6	0.419
GOLGA6L4	0.418
EXOSC3	0.417
HGC6.3	0.417
SH3BP1	0.417
CGB2	0.416
MFSD12	0.416
CCNA2	0.413
POLR2D	0.413
GOLGA8O	0.413
BYSL	0.413
RRP12	0.411
RPL9	0.41
SKIV2L2	0.41
EIF6	0.41
C19orf53	0.409
DDT	0.409
CACNA1A	0.409
PPM1D	0.408
COX7A2L	0.408
ZNF574	0.408
COPG1	0.407
CHMP4B	0.406
SLC4A1	0.403
EFTUD2	0.401
TICRR	0.401
ZNF830	0.401
TSG101	0.401
IMP3	0.4
CBWD3	0.4

Global Fraction of Cell Lines Where Essential: 555/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	22/28
blood	19/28
bone	15/26
breast	25/33
central nervous system	47/56
cervix	3/4
colorectal	13/17
esophagus	9/13
fibroblast	1/1
gastric	16/16
kidney	17/21
liver	14/20
lung	55/75
lymphocyte	12/16
ovary	21/26
pancreas	17/24
peripheral nervous system	11/16
plasma cell	7/15
prostate	1/1
skin	16/24
soft tissue	9/9
thyroid	1/2
upper aerodigestive	19/22
urinary tract	20/29
uterus	3/5

Essentiality in NALM6

Essentiality Rank: 772
Expression level (log2 read counts): 6.55

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1