Table of Contents

Hypoxia 5%O2 R04 exp191

Hypoxia 5%O2 R04 exp191

Mechanism of Action

Reduced growth oxygen

Class / Subclass 1: Environmental Stresses / Stress Condition

Screen Summary

Round: 04
Dose: N/A
Days of incubation: 12
Doublings: N/A
Numbers of reads: 12250979

Screen Results

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
3/24	Scores	View	View	View	View	View

Gene	CRANKS Score	FDR
ADK	-6.20	<0.01
FASTKD5	-3.05	0.02
UQCR10	-2.86	0.02
TBRG4	-2.60	0.08
ATP2B1	-2.58	0.08
FNDC9	-2.55	0.08
PDK3	-2.53	0.08
ZNF579	-2.47	0.09
ETV6	-2.45	0.08
SLC25A5	-2.42	0.08
DAP3	-2.39	0.08
YARS2	-2.30	0.10
ATP1A1	-2.25	0.25
C2CD4B	-2.25	0.20
ZXDB	-2.22	0.15
MCM9	-2.20	0.16
LMO2	-2.15	0.20
TMEM161B	-2.13	0.20
NUDT5	-2.12	0.25
STARD3	-2.11	0.31
SETD6	-2.11	0.20
C5orf64	-2.10	0.21
PNP	-2.09	0.21
GADD45A	-2.08	0.21
PCDHB12	-2.07	0.21
GFM2	-2.07	0.26
LIN28B	-2.06	0.21
SHOC2	-2.06	0.26
TUFM	-2.04	0.37
UBE3D	-2.03	0.22
BRD1	2.29	0.05
BRD2	2.31	0.08
LANCL2	2.31	0.08
C4orf29	2.32	0.05
TMEM135	2.32	0.05
SUCLG1	2.37	0.04
NME6	2.43	0.03
NCBP1	2.45	0.08
PYROXD1	2.48	0.12
BRMS1	2.54	0.06
PRPS1	2.57	0.03
SLC25A32	2.59	0.03
MGME1	2.65	<0.01
MTHFD2	2.77	<0.01
KLHDC2	2.83	<0.01
IPPK	2.88	<0.01
PHF6	2.91	<0.01
ZNF148	2.95	<0.01
NT5DC2	3.06	<0.01
MDH1	3.18	<0.01
SHMT2	3.21	<0.01
FAM96B	3.38	<0.01
SCAP	3.43	<0.01
PHIP	3.55	<0.01
ARID4B	3.93	<0.01
SLC25A36	4.16	<0.01
DDX3X	4.20	<0.01
STARD7	4.20	<0.01
PCGF1	4.38	<0.01
PDS5B	5.03	<0.01

Screen	Correlation	Plot
UM0131023 0.05μM R05 exp248	0.057	View
Phenformin 20μM R05 exp212	0.057	View
Doxycycline 10μM R00 exp18	0.056	View
Citral 50μM R06 exp274	0.051	View