TRIM52
Gene Information
- Official Symbol: TRIM52
- Official Name: tripartite motif containing 52
- Aliases and Previous Symbols: N/A
- Entrez ID: 84851
- UniProt: Q96A61
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| zf-C3HC4 |
| zf-B box |
GO Terms
| positive regulation of NF-kappaB transcription factor activity |
| positive regulation of DNA-binding transcription factor activity |
| nuclear body |
| regulation of DNA-binding transcription factor activity |
| zinc ion binding |
| positive regulation of molecular function |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| C14orf93 | 0.493 |
| TBC1D3G | 0.486 |
| RBBP5 | 0.483 |
| CDC73 | 0.482 |
| MYO1H | 0.475 |
| CKAP5 | 0.473 |
| TBC1D3H | 0.472 |
| SSH2 | 0.472 |
| TBC1D3C | 0.47 |
| TBC1D3 | 0.463 |
| CGB2 | 0.463 |
| PDE4DIP | 0.458 |
| COPE | 0.458 |
| MYT1L | 0.457 |
| S1PR4 | 0.452 |
| TCEB3CL2 | 0.452 |
| TBC1D3E | 0.449 |
| TBC1D3L | 0.449 |
| TBC1D3K | 0.449 |
| TBC1D3I | 0.449 |
| NPIPB8 | 0.447 |
| SEC13 | 0.447 |
| VASN | 0.445 |
| RPS9 | 0.443 |
| TBC1D3F | 0.443 |
| RRN3 | 0.437 |
| NPIPB5 | 0.432 |
| HIST2H3A | 0.431 |
| HIST2H3C | 0.43 |
| DDX56 | 0.429 |
| SNRPA1 | 0.428 |
| C1QTNF9B | 0.427 |
| CHD4 | 0.426 |
| PLK4 | 0.425 |
| POLA1 | 0.423 |
| RPS2 | 0.422 |
| MYO18A | 0.421 |
| ZNF219 | 0.42 |
| PSAP | 0.417 |
| AQR | 0.416 |
| NDC80 | 0.416 |
| CWC22 | 0.412 |
| ATXN1 | 0.412 |
| RPS7 | 0.412 |
| RFXANK | 0.411 |
| RRP15 | 0.411 |
| TCEB3C | 0.41 |
| RPS6 | 0.41 |
| NOP16 | 0.41 |
| GOLGA8O | 0.409 |
| CCNA2 | 0.408 |
| AHCTF1 | 0.407 |
| PSMB4 | 0.406 |
| EXOSC5 | 0.406 |
| RPS20 | 0.406 |
| WDR87 | 0.403 |
| PSMD11 | 0.401 |
| TFIP11 | 0.401 |
| MADCAM1 | 0.401 |
| KRT78 | 0.401 |
| PAF1 | 0.4 |
| DTL | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 0/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 1540
- Expression level (log2 read counts): 6.26
Expression Distribution
TRIM52 Expression in NALM6 Cells: 6.26
