TUBA8
Gene Information
- Official Symbol: TUBA8
- Official Name: tubulin alpha 8
- Aliases and Previous Symbols: N/A
- Entrez ID: 51807
- UniProt: Q9NY65
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the alpha tubulin protein family. Alpha tubulins are one of two core protein families (alpha and beta tubulins) that heterodimerize and assemble to form microtubules. Mutations in this gene are associated with polymicrogyria and optic nerve hypoplasia. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2010].
- UniProt Summary: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 2703
- Expression level (log2 read counts): 3.06