RPL7L1
Gene Information
- Official Symbol: RPL7L1
- Official Name: ribosomal protein L7 like 1
- Aliases and Previous Symbols: N/A
- Entrez ID: 285855
- UniProt: Q6DKI1
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ribosomal L30 |
| Ribosomal L30 N |
GO Terms
| maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) |
| maturation of LSU-rRNA |
| blastocyst formation |
| cytosolic large ribosomal subunit |
| ribosomal large subunit biogenesis |
| blastocyst development |
| structural constituent of ribosome |
| rRNA processing |
| rRNA metabolic process |
| ribosome biogenesis |
| in utero embryonic development |
| ncRNA processing |
| ribonucleoprotein complex biogenesis |
| ncRNA metabolic process |
| chordate embryonic development |
| embryo development ending in birth or egg hatching |
| nucleolus |
| RNA processing |
| anatomical structure formation involved in morphogenesis |
| embryo development |
| RNA binding |
| RNA metabolic process |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| DOCK6 | 0.491 |
| RRP15 | 0.47 |
| RPL14 | 0.465 |
| SNRNP70 | 0.459 |
| ORC6 | 0.455 |
| KCTD17 | 0.455 |
| VASN | 0.445 |
| RAD51 | 0.442 |
| CDC73 | 0.441 |
| IK | 0.439 |
| TBC1D3H | 0.439 |
| C1QTNF9B | 0.435 |
| IGFN1 | 0.432 |
| CKAP5 | 0.427 |
| RPS19BP1 | 0.426 |
| KRT78 | 0.424 |
| SLC4A1 | 0.424 |
| RPL6 | 0.423 |
| PAN3 | 0.423 |
| POLR2A | 0.421 |
| SYT9 | 0.419 |
| DTL | 0.417 |
| TFRC | 0.416 |
| RPL35 | 0.416 |
| GOLGA6A | 0.416 |
| CDC6 | 0.415 |
| TBC1D3F | 0.415 |
| PSMC1 | 0.414 |
| NUPL1 | 0.412 |
| POLE | 0.412 |
| ZFAND5 | 0.412 |
| TBC1D3 | 0.411 |
| CHAF1A | 0.409 |
| COPE | 0.409 |
| NARFL | 0.408 |
| SF3A1 | 0.408 |
| SNRNP200 | 0.407 |
| PSMA6 | 0.405 |
| POLA2 | 0.405 |
| PRPF3 | 0.404 |
| SUPT6H | 0.402 |
| TBC1D3G | 0.402 |
| WDR43 | 0.402 |
| RRN3 | 0.402 |
| PLXNB3 | 0.401 |
| RPP40 | 0.4 |
| CLN6 | 0.4 |
| PAF1 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 75/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 5/28 |
| blood | 2/28 |
| bone | 2/26 |
| breast | 5/33 |
| central nervous system | 5/56 |
| cervix | 0/4 |
| colorectal | 1/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 3/16 |
| kidney | 2/21 |
| liver | 0/20 |
| lung | 6/75 |
| lymphocyte | 1/16 |
| ovary | 2/26 |
| pancreas | 1/24 |
| peripheral nervous system | 2/16 |
| plasma cell | 2/15 |
| prostate | 0/1 |
| skin | 7/24 |
| soft tissue | 1/9 |
| thyroid | 0/2 |
| upper aerodigestive | 1/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 658
- Expression level (log2 read counts): 8.1
Expression Distribution
RPL7L1 Expression in NALM6 Cells: 8.1
