RBM26

Gene Information

Official Symbol: RBM26
Official Name: RNA binding motif protein 26
Aliases and Previous Symbols: N/A
Entrez ID: 64062
UniProt: Q5T8P6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Hydroxyurea 100μM R07 exp329	-4.36
Golgicide-A 4μM R03 exp122	-3.15
Diepoxybutane 3μM R07 exp354	-3.05
Bortezomib 0.005μM R00 exp6	-2.86
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	-2.71
UMK57 1μM R01 exp59	-2.62
CoCl2 18μM R07 exp346	-2.52
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	-2.51
ABT-702 5μM plus Deferoxamine 11μM R07 exp321	-2.49
3-Bromopyruvate 7μM R04 exp175	-2.34
CI-1040 9.5μM R08 exp472	-2.29
Quercetin 20μM R08 exp517	-2.22
Dynasore 10μM R04 exp180	-2.17
Nicotine 3000μM R08 exp510	-2.16
Dynasore 7μM R08 exp436	-2.15
Cadmium 60μM R08 exp462	-2.13
LY2090314 0.003μM R08 exp499	-2.05
MK-1775 0.32μM R02 exp75	-2.01
Bafilomycin-A1 0.009μM R08 exp454	-2
YM155 0.001μM R08 exp432	-2
Trimetrexate 0.03μM R08 exp535	-1.88
Actinomycin-D 0.001μM R00 exp3	-1.85
BI-2536 0.0042μM R03 exp95	-1.84
Vincristine 0.0005μM R04 exp190	-1.84
2-Methoxyestradiol 0.55μM R07 exp310	-1.78
ABT-702 5μM plus CoCl2 18μM R07 exp320	-1.78
Apcin 25μM plus proTAME 2μM R04 exp177	-1.78
LLY-284 2.6μM R06 exp291	-1.77
LLY-283 2.6μM R06 exp290	-1.75
Apcin 50 to 100μM on day4 R04 exp176	-1.73
Rifampicin 10μM R00 exp32	-1.71
LB-100 4.1μM R02 exp72	1.74
INK128 0.2μM R02 exp70	1.75
Pifithrin-alpha 20μM R07 exp390	1.8
LJH685 50μM R08 exp433	1.84
Amiloride 100μM R08 exp447	1.87
Vemurafenib 6.6μM R08 exp434	1.93
QNZ 0.01μM R08 exp439	1.94
Nifuroxazide 5μM R03 exp102	1.97
Tozasertib 0.1μM R07 exp414	2.02
Nutlin-3A 1.6μM R06 exp294	2.06
CCCP 1μM R00 exp11	2.13
Rapamycin 2μM R07 exp306	2.13
Dorsomorphin 5μM R07 exp357	2.16
Hypoxia 5%O2 R04 exp191	2.21
CB-5083 0.4μM R08 exp468	2.22
Doxycycline 10μM R00 exp18	2.27
6-Thio-2-deoxyguanosine 2μM R06 exp259	2.29
∆-9-Tetrahydrocannabinol 30μM R08 exp445	2.33
RO-3307 4.7μM R02 exp80	2.35
THZ531 0.225μM R08 exp444	2.35
Doxorubicin 0.02μM R08 exp478	2.36
Benzoate 10000μM R08 exp455	2.56
Salubrinal 20μM R07 exp399	2.68
Lapatinib 5μM R01 exp47	2.73
Betulinic acid 10 to 15μM on day4 R05 exp222	2.74
Rapamycin 10μM R00 exp30	3.01
Bisphenol S 100μM R08 exp458	3.07
Etoposide 0.3μM R05 exp199	3.1
Citral 75μM R06 exp275	3.22
Bisphenol A 100μM R06 exp269	3.24
Cytochalasin-B 5μM R07 exp349	3.32
Cannabidiol 20μM R08 exp466	3.84
Calcium Ionophore 0.4μM R07 exp342	4.14
Etoposide 0.1μM R05 exp198	4.29
Latrunculin-B 10μM R07 exp374	4.35
UM0129480 7μM R02 exp85	4.69
GSK626616 14μM R08 exp485	4.75
Oligomycin-A 2μM R00 exp25	5.3

Gene	Correlation
YTHDF2	0.525
ZFC3H1	0.491
HEXIM1	0.481
BRD1	0.48
PCGF1	0.463
ARID4B	0.461
RREB1	0.453
BRMS1	0.447
SAP130	0.443
CXorf56	0.429
C7orf26	0.427
ANP32A	0.417
POU2F1	0.417
ITPK1	0.417
PPIL1	0.413
CBLL1	0.413
ZBTB7A	0.411
ING1	0.408
METTL14	0.403
DPH3	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 11498
Expression level (log2 read counts): 7.73

Expression Distribution