MRPS17
Gene Information
- Official Symbol: MRPS17
- Official Name: mitochondrial ribosomal protein S17
- Aliases and Previous Symbols: N/A
- Entrez ID: 51373
- UniProt: Q9Y2R5
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
| Ribosomal S17 |
GO Terms
| mitochondrial small ribosomal subunit |
| rRNA binding |
| mitochondrial translational elongation |
| mitochondrial translational termination |
| translational termination |
| mitochondrial translation |
| translational elongation |
| cellular protein complex disassembly |
| mitochondrial gene expression |
| structural constituent of ribosome |
| protein-containing complex disassembly |
| translation |
| mitochondrial inner membrane |
| cellular component disassembly |
| peptide biosynthetic process |
| amide biosynthetic process |
| peptide metabolic process |
| cellular amide metabolic process |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| cellular macromolecule biosynthetic process |
| macromolecule biosynthetic process |
| protein-containing complex subunit organization |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| GATC | 0.561 |
| MRPL21 | 0.523 |
| VARS2 | 0.505 |
| MRPS21 | 0.504 |
| YARS2 | 0.501 |
| MRPL53 | 0.499 |
| NDUFB11 | 0.494 |
| TUFM | 0.489 |
| GFM1 | 0.487 |
| HSD17B10 | 0.487 |
| MRPS5 | 0.486 |
| TEFM | 0.48 |
| POLG | 0.478 |
| KIAA0391 | 0.478 |
| FTSJ2 | 0.473 |
| MRPS24 | 0.473 |
| MRPS16 | 0.471 |
| NARS2 | 0.469 |
| SUPV3L1 | 0.469 |
| RBFA | 0.468 |
| LARS2 | 0.467 |
| MRPS34 | 0.464 |
| NDUFA3 | 0.464 |
| C12orf65 | 0.458 |
| DAP3 | 0.458 |
| MRPL47 | 0.457 |
| MRPS14 | 0.452 |
| MRPS10 | 0.45 |
| MRPS18A | 0.447 |
| GTPBP10 | 0.445 |
| MRPS33 | 0.445 |
| NDUFB3 | 0.442 |
| UQCR10 | 0.44 |
| QRSL1 | 0.438 |
| PNPT1 | 0.437 |
| NDUFAF7 | 0.437 |
| DHRSX | 0.435 |
| MIPEP | 0.434 |
| MRPS11 | 0.434 |
| DARS2 | 0.434 |
| NDUFB6 | 0.432 |
| FASTKD5 | 0.432 |
| MRPS9 | 0.429 |
| RPUSD4 | 0.429 |
| PARS2 | 0.429 |
| EARS2 | 0.428 |
| PDSS1 | 0.427 |
| SARS2 | 0.422 |
| MRP63 | 0.42 |
| TRUB2 | 0.417 |
| MRPL23 | 0.415 |
| MRPL12 | 0.413 |
| MRPS6 | 0.412 |
| MTERFD2 | 0.411 |
| C17orf89 | 0.408 |
| NDUFS2 | 0.408 |
| NDUFA1 | 0.407 |
| GFM2 | 0.406 |
| NDUFB9 | 0.405 |
| SCO2 | 0.405 |
| WBSCR16 | 0.402 |
| C10orf2 | 0.402 |
| SELRC1 | 0.402 |
| MRPL45 | 0.401 |
| MRPL33 | 0.4 |
| MRPS7 | 0.4 |
| METTL17 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 1/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 1/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Essentiality in NALM6
- Essentiality Rank: 6639
- Expression level (log2 read counts): 4.78
Expression Distribution
MRPS17 Expression in NALM6 Cells: 4.78
