TP53TG3D [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: TP53TG3D
Official Name: TP53 target 3D
Aliases and Previous Symbols: N/A
Entrez ID: 729264
UniProt: Q9ULZ0
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: May play a significant role in p53/TP53-mediating signaling pathway. {ECO:0000269|PubMed:10534768}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Hinokiflavone 12μM R08 exp487	-2
Actinomycin-D 0.001μM R00 exp3	-1.97
Etoposide 1μM R00 exp19	-1.81
Aminopterin 0.005μM R07 exp335	1.7
Pyrazinamide 100μM R08 exp516	1.71
BH1 1μM R04 exp169	1.79
RO-3306 3 to 4μM on day4 R04 exp165	1.83
Cidofovir 10μM R07 exp345	2
ML-792 0.2μM R08 exp505	2.05
NN-Diethyl-meta-toluamide 100μM R05 exp237	2.18

Gene	Correlation
POLR2J3	0.53
PSMB4	0.51
CHD4	0.506
MFSD12	0.482
PSMD3	0.481
EXOSC9	0.468
CACTIN	0.467
CDH24	0.464
TCEB3C	0.463
TBC1D3F	0.46
RRP15	0.458
TBC1D3H	0.458
GOLGA6L1	0.458
SUPT5H	0.455
GOLGA6L3	0.451
COL2A1	0.448
TCEB3CL2	0.448
RPL6	0.448
SLC4A1	0.447
IK	0.446
TCEB3CL	0.445
CLN6	0.445
AQR	0.445
SLC6A17	0.444
PSMB2	0.444
DDTL	0.444
TBC1D3G	0.444
COPG1	0.444
CBWD3	0.443
NARFL	0.438
CEP192	0.437
RPS7	0.437
GOLGA6L4	0.436
POLR2D	0.435
AAMP	0.434
RRP7A	0.432
AATF	0.432
UTP3	0.431
OGFR	0.431
NPIPB5	0.43
SNRPA1	0.43
RPS19	0.43
GOLGA6L6	0.429
VPS28	0.428
LRR1	0.427
MT1E	0.427
RPL35	0.425
EIF4A3	0.424
RNF113A	0.424
ATP6V1B2	0.424
SAP30BP	0.423
LAD1	0.421
NOL9	0.421
KCTD17	0.421
NUPL1	0.421
CTAGE4	0.42
CCDC116	0.42
PAN3	0.42
CDCA3	0.42
PSMA6	0.42
PWP2	0.416
RANBP2	0.415
C1QTNF9B	0.415
CBWD6	0.415
SULT1A4	0.414
SULT1A3	0.414
PSMD2	0.412
POLE	0.409
NCAPG	0.408
HAP1	0.408
CBWD5	0.405
POLR2L	0.404
RBBP5	0.403
SLC38A7	0.403
COX7A2L	0.403
PBXIP1	0.403
FAM160A1	0.402
ORC6	0.402
CHMP4B	0.4
TBC1D3	0.4

Essentiality in NALM6

Essentiality Rank: 2011
Expression level (log2 read counts): -6.02

Expression Distribution

Last modified: 2026/01/07 22:37
by 127.0.0.1