Pfam Domains GO Terms
| 7tm 1 |
| olfactory receptor activity |
| detection of chemical stimulus involved in sensory perception of smell |
| sensory perception of smell |
| detection of chemical stimulus involved in sensory perception |
| detection of chemical stimulus |
| sensory perception of chemical stimulus |
| detection of stimulus involved in sensory perception |
| detection of stimulus |
| G protein-coupled receptor activity |
| sensory perception |
| G protein-coupled receptor signaling pathway |
| nervous system process |
| system process |
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
| Gene | Correlation |
|---|---|
| ANKLE2 | 0.514 |
| TWISTNB | 0.503 |
| PSMB4 | 0.491 |
| CHD4 | 0.49 |
| C14orf93 | 0.485 |
| NUPL1 | 0.475 |
| RBBP5 | 0.474 |
| LRR1 | 0.474 |
| TFIP11 | 0.473 |
| RANBP2 | 0.472 |
| DDTL | 0.471 |
| RPL35 | 0.47 |
| ATP6AP1 | 0.468 |
| CBWD5 | 0.466 |
| CBWD3 | 0.464 |
| PSMD11 | 0.463 |
| STIL | 0.462 |
| AAMP | 0.462 |
| VASN | 0.46 |
| RBM39 | 0.457 |
| C1QTNF9B | 0.457 |
| CBWD6 | 0.456 |
| TCEB3C | 0.456 |
| SUPT5H | 0.454 |
| IK | 0.453 |
| CEP192 | 0.453 |
| CDC45 | 0.453 |
| SULT2B1 | 0.453 |
| UTP3 | 0.453 |
| SAP30BP | 0.452 |
| MYO1H | 0.451 |
| SYT9 | 0.45 |
| TICRR | 0.449 |
| ATP6V1C1 | 0.448 |
| RPS2 | 0.448 |
| TCEB3CL2 | 0.446 |
| PSMA6 | 0.445 |
| HIST1H4B | 0.443 |
| COPA | 0.442 |
| KRT78 | 0.441 |
| NPIPB5 | 0.441 |
| TBC1D3H | 0.441 |
| NOL8 | 0.439 |
| FAM86B2 | 0.437 |
| SLC4A1 | 0.437 |
| TGM5 | 0.434 |
| TSPY8 | 0.432 |
| ORC1 | 0.431 |
| AKIRIN2 | 0.43 |
| CACTIN | 0.43 |
| FAM160A1 | 0.429 |
| ZNF106 | 0.429 |
| UBAP1 | 0.428 |
| SNIP1 | 0.428 |
| RAD21 | 0.426 |
| COL2A1 | 0.424 |
| ISCU | 0.424 |
| PSMC1 | 0.423 |
| TCEB3CL | 0.423 |
| NOL10 | 0.423 |
| DTL | 0.422 |
| HAP1 | 0.422 |
| XYLT2 | 0.42 |
| ARCN1 | 0.419 |
| RPL34 | 0.419 |
| PARP3 | 0.418 |
| CCNA2 | 0.417 |
| POLA1 | 0.417 |
| ORC6 | 0.416 |
| TBC1D3F | 0.416 |
| COPZ1 | 0.416 |
| RPS28 | 0.415 |
| EXOSC9 | 0.415 |
| DOCK6 | 0.414 |
| RPS19BP1 | 0.414 |
| FAM231C | 0.413 |
| SUPT6H | 0.413 |
| FAM231A | 0.413 |
| CDC73 | 0.412 |
| TBC1D3 | 0.412 |
| KCTD17 | 0.412 |
| FBXW9 | 0.412 |
| TBC1D3G | 0.411 |
| COPB1 | 0.411 |
| THOC1 | 0.41 |
| PCF11 | 0.409 |
| UTP20 | 0.409 |
| CHAF1A | 0.409 |
| PRPF8 | 0.409 |
| NBPF10 | 0.409 |
| SF3A3 | 0.407 |
| MT1E | 0.407 |
| PSMC6 | 0.405 |
| GOLGA8O | 0.404 |
| TOP1MT | 0.403 |
| NOP16 | 0.403 |
| EGR2 | 0.402 |
| RPL8 | 0.402 |
| DNM2 | 0.401 |
| TBC1D3L | 0.401 |
| EXOSC6 | 0.401 |
| TBC1D3I | 0.4 |
| CDCA5 | 0.4 |
| TBC1D3K | 0.4 |
| PLK1 | 0.4 |
| TBC1D3E | 0.4 |
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 0/28 |
| blood | 0/28 |
| bone | 0/26 |
| breast | 0/33 |
| central nervous system | 0/56 |
| cervix | 0/4 |
| colorectal | 0/17 |
| esophagus | 0/13 |
| fibroblast | 0/1 |
| gastric | 0/16 |
| kidney | 0/21 |
| liver | 0/20 |
| lung | 0/75 |
| lymphocyte | 0/16 |
| ovary | 0/26 |
| pancreas | 0/24 |
| peripheral nervous system | 0/16 |
| plasma cell | 0/15 |
| prostate | 0/1 |
| skin | 0/24 |
| soft tissue | 0/9 |
| thyroid | 0/2 |
| upper aerodigestive | 0/22 |
| urinary tract | 0/29 |
| uterus | 0/5 |
Expression Distribution