RFT1
Gene Information
- Official Symbol: RFT1
- Official Name: RFT1 homolog
- Aliases and Previous Symbols: N/A
- Entrez ID: 91869
- UniProt: Q96AA3
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes an enzyme which catalyzes the translocation of the Man(5)GlcNAc (2)-PP-Dol intermediate from the cytoplasmic to the luminal side of the endoplasmic reticulum membrane in the pathway for the N-glycosylation of proteins. Mutations in this gene are associated with congenital disorder of glycosylation type In.[provided by RefSeq, Dec 2008].
- UniProt Summary: May be involved in N-linked oligosaccharide assembly. May participate in the translocation of oligosaccharide from the cytoplasmic side to the lumenal side of the endoplasmic reticulum membrane. {ECO:0000269|PubMed:18313027}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 659
- Expression level (log2 read counts): 5.68
RFT1 Expression in NALM6 Cells: 5.68
