GTPBP8

Gene Information

Official Symbol: GTPBP8
Official Name: GTP binding protein 8 (putative)
Aliases and Previous Symbols: N/A
Entrez ID: 29083
UniProt: Q8N3Z3
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Mubritinib 0.2μM R02 exp65	1.7
2-Methoxyestradiol 0.55μM R07 exp310	1.76
UMK57 1μM R01 exp59	1.76
UM0125461 0.74μM R02 exp84	1.88
Thimerosal 0.85μM R08 exp529	1.92
Tubastatin-A 2.5μM R07 exp417	2.06
Oligomycin-A 2μM R00 exp25	2.22
Hydroxyurea 100μM R07 exp329	2.37

Gene	Correlation
MALSU1	0.542
PET112	0.533
NDUFB10	0.525
ACAD9	0.515
FTSJ2	0.513
NDUFB11	0.51
NDUFA2	0.505
MTIF2	0.505
PET117	0.504
GRSF1	0.504
NSUN4	0.499
MRPS21	0.498
NDUFC1	0.497
ERAL1	0.494
RNMTL1	0.488
GTPBP10	0.481
LARS2	0.48
CARS2	0.477
NDUFA1	0.477
MRPL3	0.474
NUBPL	0.474
TIMMDC1	0.473
PDE12	0.473
HSD17B10	0.472
MTO1	0.472
DARS2	0.471
TFB1M	0.471
MRPS12	0.468
QRSL1	0.468
PARS2	0.467
NDUFAF7	0.463
MRPS35	0.458
MRPS16	0.456
METTL17	0.456
FASTKD2	0.456
NARS2	0.453
NDUFB6	0.453
DDX28	0.451
RPUSD3	0.447
NDUFA11	0.447
MRPS26	0.446
RARS2	0.445
COX11	0.445
COA3	0.442
NDUFS2	0.442
NDUFB4	0.441
POLRMT	0.441
GFM1	0.441
MRPL43	0.44
MRPL21	0.439
PTCD3	0.439
MRPL28	0.439
EARS2	0.439
YARS2	0.436
MTRF1L	0.433
CHCHD1	0.432
MRPL45	0.431
MRPS18B	0.431
NDUFS5	0.431
NDUFB9	0.428
SFXN4	0.428
MCAT	0.427
TARS2	0.426
MARS2	0.424
ICT1	0.424
GTPBP6	0.423
RTN4IP1	0.422
MRPS34	0.42
SSBP1	0.418
MRPS27	0.418
MRPL39	0.418
NDUFC2	0.416
MRPL37	0.416
MRPL53	0.415
MRPS25	0.415
MRPL49	0.414
NDUFAF3	0.413
MRPS22	0.412
TRUB2	0.412
MTG2	0.409
VARS2	0.409
NDUFA3	0.408
AARS2	0.407
NDUFAF5	0.407
MRPL17	0.406
COA6	0.406
NDUFAF6	0.405
TMEM261	0.405
WBSCR16	0.405
MRPS7	0.404
MRPL23	0.402
NDUFV2	0.401
XPNPEP3	0.401
NDUFA6	0.401
C1QBP	0.401
MRP63	0.4

Global Fraction of Cell Lines Where Essential: 0/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 1043
Expression level (log2 read counts): 4.3

Expression Distribution