Lead acetate 2000μM R08 exp498 no dilution day6

Industrial pollutant, heavy metal toxin

PubChem Name: Lead acetate trihydrate
Synonyms: N/A
CAS #: 6080-56-4
PubChem CID: 22456
IUPAC: lead(2+);diacetate;trihydrate
INCHI Name: InChI=1S/2C2H4O2.3H2O.Pb/c2*1-2(3)4;;;;/h2*1H3,(H,3,4);3*1H2;/q;;;;;+2/p-2
INCHI Key: MCEUZMYFCCOOQO-UHFFFAOYSA-L
Molecular Weight: 379
Canonical SMILES: CC(=O)[O-].CC(=O)[O-].O.O.O.[Pb+2]
Isomeric SMILES: N/A
Molecular Formula: C4H12O7Pb

Pb(CH3COO)2 3H2O

Sensitive/Resistant hits (FDR<0.05)	CRANKS	Score Plot	Top 30 Genes	Screen Similarity	Top 30 Sensitive GO terms	Top 30 Resistant GO terms
21/63	Scores	View	View	View	View	View

Screen	Correlation	Plot
Radicicol 0.16μM R05 exp242	0.075	View
Thapsigargin 0.005μM R07 exp407	0.075	View
Sulforaphane 9μM R08 exp525	0.069	View
iCRT14 30μM R08 exp492	0.066	View
Sulforaphane 9μM R08 exp526 no dilution day6	0.065	View
Milciclib 2μM R08 exp502	0.06	View
Trimetrexate 0.03μM R08 exp535	0.058	View
Quercetin 20μM R08 exp517	0.057	View
MS023 2μM R03 exp134	0.056	View
Rapamycin 10μM R00 exp30	0.056	View
TRAIL 50ng/ml R00 exp36	0.055	View
Nutlin-3A 1.6μM R06 exp294	0.055	View
Olaparib 4μM R08 exp512	0.054	View
Rucaparib 6.5μM R08 exp520	0.051	View
Lead acetate 2000μM R08 exp497	0.36	View
Ethanol 0.01 R05 exp234	0.108	View
GSK626616 14μM R08 exp485	0.07	View
B02 10μM R08 exp453	0.069	View
Calcium Ionophore 0.4μM R07 exp342	0.068	View
Hippuristanol 0.12μM R08 exp489 no dilution day6	0.061	View
Benzoate 20000μM R08 exp456	0.058	View
Hippuristanol 0.12μM R08 exp488	0.057	View
Diepoxybutane 3μM R07 exp354	0.056	View
AICAR 240μM R03 exp116	0.054	View
FK-506 30μM R07 exp359	0.052	View
I-BRD9 4μM R07 exp365	0.051	View
All-trans-Retinoic-Acid 40μM R07 exp334	0.051	View

GO Term	Fold Change	Genes
negative regulation of long-chain fatty acid import into cell	368.20	AKT2,AKT1
negative regulation of long-chain fatty acid import across plasma membrane	368.20	AKT2,AKT1
Sin3-type complex	105.20	ING1,ARID4B,BRMS1,SAP130
Sin3 complex	105.20	ING1,ARID4B,BRMS1,SAP130
negative regulation of stem cell population maintenance	92.05	ING1,ARID4B,BRMS1,SAP130
myelination in peripheral nervous system	63.73	AKT2,NF1,AKT1
peripheral nervous system axon ensheathment	63.73	AKT2,NF1,AKT1
Schwann cell development	57.13	AKT2,NF1,AKT1
positive regulation of stem cell population maintenance	47.00	ING1,ARID4B,BRMS1,SAP130
regulation of stem cell population maintenance	31.56	ING1,ARID4B,BRMS1,SAP130
histone deacetylase complex	27.62	ING1,ARID4B,BRMS1,SAP130
negative regulation of transforming growth factor beta receptor signaling pathway	24.55	ING1,ARID4B,BRMS1,SAP130
regulation of peptidyl-serine phosphorylation	21.08	MAPKAP1,RICTOR,BAK1,AXIN1,AKT1
regulation of transforming growth factor beta receptor signaling pathway	20.31	ING1,ARID4B,BRMS1,AXIN1,SAP130
regulation of cellular response to transforming growth factor beta stimulus	19.87	ING1,ARID4B,BRMS1,AXIN1,SAP130
negative regulation of cell migration	11.96	ING1,ARID4B,BRMS1,NF1,AKT1,SAP130
negative regulation of cell motility	11.35	ING1,ARID4B,BRMS1,NF1,AKT1,SAP130
negative regulation of locomotion	10.13	ING1,ARID4B,BRMS1,NF1,AKT1,SAP130
regulation of protein phosphorylation	6.63	MAPKAP1,HEXIM1,RICTOR,BAK1,AXIN1,AKT2,NF1,AKT1,PIH1D1,EIF2AK3,PHIP