NBPF10 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: NBPF10
Official Name: NBPF member 10
Aliases and Previous Symbols: N/A
Entrez ID: 100132406
UniProt: Q6P3W6
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Ammonium tetrathiomolybdate 10μM R08 exp448	-1.73
BAY-598 4μM R05 exp220	1.77
Losmapimod 1μM R07 exp376	1.77
A-769662 20μM R07 exp331	1.81
CVT-10216 0.1μM R06 exp278	1.89
Selumetinib 20μM R02 exp81	2.41

Gene	Correlation
TBC1D3G	0.522
PRIM1	0.515
TWISTNB	0.505
MED17	0.497
CDC6	0.492
MYO1H	0.491
ORC1	0.49
TBC1D3C	0.489
AKIRIN2	0.484
CBWD3	0.484
TFIP11	0.484
CHMP2A	0.48
TBC1D3H	0.479
SUPT6H	0.476
POLA2	0.476
TBC1D3F	0.475
TBC1D3	0.474
DNTTIP2	0.473
CBWD6	0.472
COPB1	0.471
PCF11	0.469
RPL14	0.469
DDTL	0.468
TCEB3CL2	0.468
CBWD5	0.467
C14orf93	0.467
TICRR	0.467
NUPL1	0.466
C1QTNF9B	0.465
ZFAND5	0.463
POLR2A	0.46
SF3A3	0.458
PSMD11	0.456
RBBP5	0.454
CACTIN	0.452
NOL10	0.452
PAF1	0.451
HAP1	0.449
CHD4	0.448
MT1E	0.445
PSMD1	0.443
RRP15	0.443
CDC45	0.443
PSMA6	0.442
UPF1	0.442
TAGLN	0.441
TCEB3C	0.44
KCTD17	0.44
CDC73	0.44
SSH2	0.438
COPG1	0.438
PSMB2	0.438
TBC1D3I	0.436
ORC6	0.436
TBC1D3K	0.436
SLC6A17	0.436
TBC1D3L	0.436
TBC1D3E	0.436
RPS3A	0.436
PSMD3	0.435
RNASE3	0.434
ANKLE2	0.434
RPS12	0.433
INTS6	0.432
TCEB3CL	0.432
VASN	0.431
PSMC1	0.431
ATP6V1C1	0.43
RRN3	0.429
CTAGE4	0.428
TOPBP1	0.428
RANBP2	0.427
SMG1	0.427
RIOK2	0.427
PSMB4	0.427
MYB	0.427
NUP107	0.426
PSMC5	0.425
TSPY1	0.424
RPL34	0.423
RPL35	0.422
ATP6V0B	0.422
RAD21	0.42
ELMOD3	0.42
CTR9	0.419
BYSL	0.419
PSMC6	0.418
RILPL2	0.417
SMG7	0.416
PSMD6	0.416
OGFR	0.416
SCAF1	0.416
WDR43	0.413
SYT9	0.413
ATP6AP2	0.412
GOLGA6L6	0.412
DTL	0.412
CEP192	0.412
CCDC116	0.41
VPS54	0.41
PWP2	0.41
OR10G3	0.409
NUP205	0.409
SLC4A1	0.408
GOLGA8O	0.408
RPS2	0.407
DDX56	0.406
RNF121	0.406
SHFM1	0.404
TOP1MT	0.404
RAD51	0.403
PSMD14	0.403
POLR2J3	0.403
PSMB1	0.402
ZNF106	0.402
SEC13	0.402
DIDO1	0.401
ARCN1	0.401
RNF113A	0.4
DNM2	0.4
GPRIN2	0.4
HIST2H2BF	0.4

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	1/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 2043
Expression level (log2 read counts): 5.86

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1