XPNPEP3
Gene Information
- Official Symbol: XPNPEP3
- Official Name: X-prolyl aminopeptidase 3
- Aliases and Previous Symbols: N/A
- Entrez ID: 63929
- UniProt: Q9NQH7
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known.[provided by RefSeq, Mar 2011].
- UniProt Summary: N/A
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 535
- Expression level (log2 read counts): 5.86
XPNPEP3 Expression in NALM6 Cells: 5.86
