TP53TG3B

Gene Information

Official Symbol: TP53TG3B
Official Name: TP53 target 3B
Aliases and Previous Symbols: N/A
Entrez ID: 729355
UniProt: Q9ULZ0
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: N/A
UniProt Summary: May play a significant role in p53/TP53-mediating signaling pathway. {ECO:0000269|PubMed:10534768}.

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Gene	Correlation
TCEB3C	0.55
CHD4	0.537
PSMB4	0.522
TCEB3CL2	0.518
TCEB3CL	0.518
SLC6A17	0.516
MT1E	0.515
KCTD17	0.515
NPIPB5	0.509
PSMD3	0.509
SLC4A1	0.508
TWISTNB	0.503
DDTL	0.503
MFSD12	0.501
ATP6V1B2	0.493
IK	0.488
CACTIN	0.487
C1QTNF9B	0.486
ATXN1	0.486
COL2A1	0.483
TBC1D3G	0.482
CTAGE4	0.48
NUPL1	0.479
SUPT5H	0.477
CBWD3	0.476
RPS19	0.474
SAP30BP	0.473
ANKLE1	0.472
PSMB2	0.472
RPS19BP1	0.47
TBC1D3H	0.469
AAMP	0.469
GOLGA6L6	0.468
GOLGA6A	0.468
ATP6V1A	0.468
GOLGA6L3	0.467
GOLGA8O	0.467
POLR2D	0.467
DHX38	0.463
COPA	0.462
FOXD4L2	0.462
COPG1	0.461
DDT	0.459
DOCK6	0.456
HIVEP3	0.456
GOLGA6L4	0.455
PBXIP1	0.455
AATF	0.455
SH3BP1	0.454
FAM160A1	0.454
UPF1	0.453
CHMP4B	0.453
OSBP	0.452
TICRR	0.452
KRT78	0.451
MED15	0.45
EXOSC6	0.449
RPS12	0.447
UTP3	0.446
IGFN1	0.444
NOL10	0.444
ACSF2	0.443
TFIP11	0.443
NUP205	0.442
ATP6V1C1	0.441
PAN3	0.441
EXOSC5	0.441
CTAGE9	0.44
SLC5A5	0.44
PAN2	0.44
TBC1D3F	0.439
NSF	0.439
CBWD5	0.439
CEP192	0.438
RPL6	0.438
PSMC2	0.438
ORC6	0.437
RBBP5	0.436
WDR75	0.436
ORC1	0.436
RPL34	0.435
POLR2J3	0.435
TSG101	0.435
VPS28	0.435
PSMD2	0.434
ATP6V0B	0.434
FCN2	0.434
CDH24	0.433
LRR1	0.433
CBWD6	0.432
PSMA6	0.432
ZFAND5	0.43
EGR2	0.43
SUPT6H	0.429
HGC6.3	0.429
AQR	0.428
ALDH1B1	0.428
ZNF830	0.427
SF3A3	0.425
POLA1	0.425
EXOSC8	0.425
POLE	0.424
COPB1	0.423
VASN	0.423
NOL9	0.423
RRP15	0.422
HINFP	0.422
RNF113A	0.421
GAR1	0.421
C14orf93	0.42
PSMA7	0.42
NUP160	0.42
OGFR	0.419
ATP6AP2	0.418
MYH7B	0.418
RPL35	0.418
CCDC116	0.418
LAD1	0.418
SF3A2	0.417
VPS54	0.417
SMTN	0.417
RPLP0	0.417
GOLGA6L1	0.416
PWP2	0.416
NARFL	0.415
PPP1R13L	0.415
SYT9	0.415
SNRPA1	0.414
RPS7	0.414
RNPC3	0.414
HNRNPA1	0.413
AKT1S1	0.413
EIF4A3	0.413
WDR87	0.413
NAPA	0.413
PSMB3	0.412
SEC13	0.412
AKIRIN2	0.412
TIMELESS	0.411
TYMS	0.41
PIGS	0.409
MFRP	0.409
INTS5	0.409
POLR1A	0.408
SART1	0.408
CCNA2	0.407
RFPL3	0.407
KIF3C	0.407
DNTTIP2	0.406
CLN6	0.405
TSPY8	0.404
MAP7D1	0.403
SPRR2B	0.403
DISP2	0.403
TRAPPC11	0.402
FBL	0.402
EIF3A	0.401
XAB2	0.4
RNF121	0.4

Essentiality in NALM6

Essentiality Rank: 2003
Expression level (log2 read counts): -6.6

Expression Distribution

Screen	Score
DABN 20μM R00 exp17	-1.86
Ammonium tetrathiomolybdate 10μM R08 exp448	-1.7
CVT-10216 0.1μM R06 exp278	1.77
Cidofovir 10μM R07 exp345	1.86