CXorf56

Gene Information

Official Symbol: CXorf56
Official Name: chromosome X open reading frame 56
Aliases and Previous Symbols: N/A
Entrez ID: 63932
UniProt: Q9H5V9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: N/A

Function Summary

Entrez Summary: While this gene is well-supported by transcript data, no functional information on its protein products is currently available. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009].
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Cyclosporin-A 3μM R07 exp348	-2.73
THZ531 0.11 to 0.125μM on day4 R07 exp410	-2.68
THZ531 0.11 to 0.125 to 0.35μM on day4 then day6 R07 exp412	-2.48
Ethambutol 25μM R08 exp481	-2.47
Rifampicin 30μM R08 exp430	-2.38
Cycloheximide 0.02μM R00 exp14	-2.27
Dynasore 10μM R04 exp180	-2.23
THZ531 0.11 to 0.175μM on day4 R07 exp413	-2.21
3-Bromopyruvate 7μM R04 exp175	-2.12
THZ531 0.11μM R07 exp409	-2.09
IU1-47 25μM R04 exp182	-2.07
BI-6727 0.0125μM R03 exp97	-2
Cadmium 60μM R08 exp462	-2
Tunicamycin 0.04μM R07 exp418	-1.98
UM0130462 0.025 to 0.035μM day4 R05 exp247	-1.92
ETC-159 50μM R08 exp480	-1.89
UM0011500 5μM R05 exp245	-1.89
Hypoxia 5%O2 R04 exp191	-1.88
Cyclosporin-A 0.8μM R07 exp347	-1.88
Parthenolide 2.5μM R05 exp238	-1.86
PNU96415E 10μM R03 exp145	-1.83
2-Methoxyestradiol 0.55μM R07 exp310	-1.74
JQ1 0.01μM R03 exp130	-1.74
Cincreasin 100μM R08 exp473	-1.72
Bafilomycin-A1 0.009μM R08 exp454	-1.71
Latrunculin-B 10μM R07 exp374	1.7
Trametinib 10μM R02 exp83	1.71
RO-3307 4.7μM R02 exp80	1.71
Fluvastatin 2.2μM R06 exp282	1.72
JQ1 0.8μM R08 exp435	1.74
BI-2536 0.02μM R03 exp96	1.76
RK-33 8μM R08 exp518	1.77
Vinblastine 0.2μM R03 exp108	1.79
Rapamycin 2μM plus Cyclosporin-A 3μM R07 exp307	1.8
DABN racemic mixture R03 exp93	1.8
HMS-I1 10μM R06 exp256	1.8
WYE-354 6μM R02 exp90	1.8
AICAR 240μM R03 exp116	1.85
Oligomycin-A 2μM R00 exp25	1.86
INK128 0.2μM R02 exp70	1.9
Nutlin-3A 1.6μM R06 exp294	1.91
Vemurafenib 6.6μM R08 exp434	1.91
Erlotinib 10μM R05 exp216	1.92
Tanespimycin 14μM R08 exp527	1.92
QNZ 0.01μM R08 exp439	1.93
CB-5083 0.4μM R08 exp468	1.94
Senexin-A 25μM R07 exp400	1.98
Lead acetate 2000μM R08 exp497	2.05
QNZ 0.01μM R05 exp241	2.09
Cannabidiol 13μM R08 exp465	2.11
CI-1040 9.5μM R08 exp472	2.12
KU-0063794 3.8μM R02 exp71	2.15
Arsenic trioxide 60μM R08 exp449	2.21
Rapamycin 2μM R07 exp306	2.21
Bisphenol S 100μM R08 exp458	2.25
MK2206 4μM R08 exp504	2.35
Rapamycin 0.001μM R08 exp429	2.49
Arsenate 40μM R06 exp264	2.58
Doxorubicin 0.02μM R08 exp478	2.59
GSK626616 14μM R08 exp485	2.59
I-BRD9 4μM R07 exp365	2.59
Thimerosal 0.85μM R08 exp529	2.62
Rapamycin 2μM plus FK-506 5μM R07 exp308	2.64
2-Deoxy-D-glucose 800μM R05 exp214	2.67
Calcium Ionophore 0.4μM R07 exp342	2.68
∆-9-Tetrahydrocannabinol 30μM R08 exp445	2.69
Lead acetate 2000μM R08 exp498 no dilution day6	2.78
HMS-I2 10μM R06 exp288	2.92
Milciclib 2μM R08 exp502	3.14
Mubritinib 0.2μM R02 exp65	3.21
Rapamycin 10μM R00 exp30	3.48
Rapamycin 1μM R00 exp29	3.68
iCRT14 30μM R08 exp492	3.72
Staurosporine 0.02μM R08 exp524	4.32
Cannabidiol 20μM R08 exp466	4.39

Gene	Correlation
PTAR1	0.489
GEMIN7	0.482
C11orf57	0.47
KDM8	0.47
CBLL1	0.465
METTL14	0.457
FH	0.454
PDCD6IP	0.45
RABGGTB	0.45
PPP6C	0.448
PGM3	0.446
DPH1	0.438
DHRSX	0.436
C16orf80	0.435
WDR83	0.434
RPP21	0.43
RBM26	0.429
URM1	0.428
PPCS	0.423
PPCDC	0.422
PRKRIP1	0.418
DPH5	0.417
GEMIN6	0.417
ZCRB1	0.416
PMVK	0.414
C15orf41	0.413
RPIA	0.407
ZNHIT1	0.405
FKBPL	0.404

Global Fraction of Cell Lines Where Essential: 11/694

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/26
bone	0/26
breast	0/30
central nervous system	0/49
cervix	0/4
colorectal	0/17
esophagus	0/11
fibroblast	0/1
gastric	0/14
kidney	0/18
liver	1/19
lung	1/72
lymphocyte	0/16
ovary	0/25
pancreas	0/22
peripheral nervous system	0/15
plasma cell	0/12
prostate	0/1
skin	0/20
soft tissue	0/9
thyroid	0/2
upper aerodigestive	2/22
urinary tract	0/28
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 6384
Expression level (log2 read counts): 5.08

Expression Distribution