NOP16 [The Human Chemical-Genetic Interaction Map Project]

Gene Information

Official Symbol: NOP16
Official Name: NOP16 nucleolar protein
Aliases and Previous Symbols: N/A
Entrez ID: 51491
UniProt: Q9Y3C1
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Trientine 500μM R08 exp534	-2.16
MS023 7μM R03 exp135	-1.98
CR131-b 0.005μM R08 exp474	-1.87
Atovaquone 15μM R08 exp451	-1.81
Milciclib 2μM R08 exp502	-1.78
Trichostatin-A 0.06μM R07 exp415	1.7
MSC2530818 10μM R07 exp379	1.71
Nicotinamide 1000μM R03 exp101	1.72
Celastrol 0.12μM R05 exp225	1.84
Ibrutinib 10μM R08 exp442	1.84
Asunaprenir 3μM R07 exp336	1.87
CyclicAMP 200μM R08 exp475	1.96
Erlotinib 10μM R05 exp216	1.96
Nifurtimox 1μM R03 exp141	2.02
Cycloheximide 0.02μM R00 exp14	2.03
Nifuroxazide 1μM R01 exp51	2.06
UM0131023 0.05μM R05 exp248	2.13
PFI-2 4μM R05 exp239	2.16
Demecolcine 0.03μM R05 exp228	2.18
Hydroxyurea 15μM R06 exp289	2.2
proTAME 5μM R04 exp187	2.21
Cyclosporin-A 3μM R07 exp348	2.25
GSK343 3μM R03 exp124	2.25
SB202190 10μM R03 exp148	2.39
BRD2 inhibitor II 20μM R07 exp341	2.53
Taxol 0.002μM R01 exp54	2.68
Alpha-Amanitin 0.5μM R00 exp5	2.74

Gene	Correlation
TBC1D3H	0.522
RPS2	0.522
CHD4	0.515
TBC1D3G	0.505
PSMA6	0.501
SCAF1	0.501
RPS28	0.495
PSMD11	0.492
RPS7	0.489
PAN3	0.489
GOLGA6L1	0.488
DDTL	0.487
ZFAND5	0.487
PSMB4	0.482
SUPT6H	0.482
TAF1	0.479
CDT1	0.479
AAMP	0.478
RBBP5	0.477
TBC1D3F	0.473
RPS12	0.473
NPIPB8	0.473
MYT1L	0.471
TCEB3CL2	0.47
CCNA2	0.469
CBWD3	0.468
SLC6A17	0.467
ORC6	0.467
PSMD14	0.467
PSMA7	0.467
RAD51	0.467
CBWD5	0.465
NDC80	0.465
TBC1D3I	0.465
TBC1D3E	0.465
TBC1D3L	0.465
TBC1D3K	0.465
NOL10	0.463
VASN	0.463
PCF11	0.463
MT1E	0.463
KCTD17	0.462
NUPL1	0.462
DTL	0.462
DISP2	0.461
NPIPB5	0.459
TBC1D3C	0.458
ZNF106	0.455
MYO1H	0.454
RPS3A	0.453
MYB	0.453
DDX56	0.452
SMG7	0.452
C14orf93	0.452
PAF1	0.45
C1QTNF9B	0.449
PSMD1	0.447
TBC1D3	0.446
ATXN1	0.444
RANBP2	0.443
S1PR4	0.441
RPS9	0.44
RNF121	0.439
EXOSC5	0.438
UQCRH	0.438
TWISTNB	0.437
SMG1	0.436
PPM1D	0.435
RPL14	0.434
TCEB3C	0.434
KRT2	0.433
SSH2	0.433
RPL35	0.432
RFFL	0.432
HIVEP3	0.431
FCN2	0.43
COPG1	0.43
CTR9	0.429
SF3A3	0.429
RRN3	0.428
PAN2	0.428
SFPQ	0.427
XYLT2	0.427
UTP3	0.426
SNIP1	0.426
MED14	0.426
AKIRIN2	0.424
TCEB3CL	0.423
POLR2J3	0.423
POLE	0.423
TSPY8	0.422
PSMC2	0.419
ZNF830	0.418
CDC73	0.417
RPS11	0.417
ART5	0.416
NARFL	0.416
TOP1MT	0.416
TIMELESS	0.415
LRR1	0.415
MED17	0.415
GOSR2	0.415
RRM1	0.413
TERF1	0.412
SLC4A1	0.412
PARP3	0.412
PSMB1	0.41
TRIM52	0.41
RPL30	0.41
ISCU	0.409
ORC1	0.409
PPFIA4	0.408
AQR	0.408
SSFA2	0.408
COPB1	0.408
CCDC64B	0.407
FAM86B2	0.407
CBWD6	0.407
RPS20	0.407
PSMD8	0.407
RFXANK	0.406
WDR43	0.406
HIST2H3A	0.405
ZNF655	0.404
HIST2H3C	0.404
ADRM1	0.404
OGFR	0.403
OR10G3	0.403
MDM2	0.403
NUP133	0.403
COPE	0.403
EXOSC9	0.402
HINFP	0.402
DDT	0.401
GOLGA6L6	0.401
PSMC1	0.401
TERF2	0.4
UPF1	0.4

Global Fraction of Cell Lines Where Essential: 651/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	1/1
909776.0	1/1
bile duct	25/28
blood	25/28
bone	25/26
breast	26/33
central nervous system	52/56
cervix	3/4
colorectal	15/17
esophagus	13/13
fibroblast	1/1
gastric	15/16
kidney	21/21
liver	17/20
lung	62/75
lymphocyte	14/16
ovary	23/26
pancreas	22/24
peripheral nervous system	15/16
plasma cell	13/15
prostate	1/1
skin	23/24
soft tissue	8/9
thyroid	2/2
upper aerodigestive	17/22
urinary tract	25/29
uterus	4/5

Essentiality in NALM6

Essentiality Rank: 314
Expression level (log2 read counts): 5.98

Expression Distribution

Last modified: 2026/01/07 22:36
by 127.0.0.1