MRPS23

Gene Information

Official Symbol: MRPS23
Official Name: mitochondrial ribosomal protein S23
Aliases and Previous Symbols: N/A
Entrez ID: 51649
UniProt: Q9Y3D9
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
42°C R08 exp539	1.75
iCRT14 30μM R08 exp492	1.79
Actinomycin-D 0.001μM R00 exp3	1.8
LLY-283 2.6μM R06 exp290	1.84
Chloroquine 32μM R08 exp470	1.88
WYE-354 6μM R02 exp90	1.95
Ammonium tetrathiomolybdate 10μM R08 exp448	1.97
Oligomycin-A 2μM R00 exp25	2.09
GSK-J4 1.5μM R08 exp441	2.62

Gene	Correlation
MRP63	0.63
HSD17B10	0.591
MRPL21	0.586
COX16	0.569
VARS2	0.568
MRPS14	0.567
GFM1	0.566
DAP3	0.566
RPUSD4	0.563
MRPS6	0.551
SUPV3L1	0.55
YARS2	0.546
QRSL1	0.545
NDUFA3	0.545
MRPL23	0.544
TARS2	0.538
PARS2	0.534
FARS2	0.529
MRPS9	0.528
HARS2	0.527
SCO2	0.527
EARS2	0.526
DARS2	0.526
SELRC1	0.525
BCS1L	0.525
NARS2	0.524
MRPS16	0.522
WBSCR16	0.522
COQ2	0.522
PNPT1	0.52
SARS2	0.519
MRPS21	0.51
KIAA0391	0.508
LARS2	0.507
GTPBP10	0.507
TUFM	0.505
MRPS34	0.504
MRPS18A	0.503
UQCRC2	0.501
MRPL15	0.501
MRPS10	0.499
GFM2	0.499
MRPS26	0.498
MRPS5	0.498
MRPS25	0.497
MRPL47	0.496
C12orf65	0.496
COX7B	0.494
MRPS7	0.493
WARS2	0.49
POLG2	0.488
MRPL20	0.486
C10orf2	0.484
NDUFAF7	0.484
METTL17	0.483
MRPL42	0.483
RARS2	0.482
TFAM	0.482
NDUFA1	0.477
NDUFB11	0.477
MRPL44	0.476
NDUFC2	0.476
MRPL45	0.476
NDUFS7	0.475
MRPL53	0.475
MRPL39	0.475
FASTKD5	0.474
MTRF1L	0.473
AARS2	0.473
CHCHD4	0.473
TRUB2	0.471
RNMTL1	0.471
MRPL22	0.467
SLC25A26	0.465
MRPS24	0.464
MRPS11	0.463
MRPL36	0.462
RBFA	0.461
MRPL33	0.459
FTSJ2	0.457
MRPL4	0.454
ATP5D	0.453
MRPL55	0.452
ATP5A1	0.45
NDUFA2	0.45
MRPL3	0.447
TEFM	0.447
PET112	0.446
MTG2	0.446
MTERFD2	0.444
TFB1M	0.443
RNASEH1	0.442
NDUFV1	0.442
COX15	0.442
MARS2	0.44
COA6	0.436
NDUFAF4	0.434
MRPL13	0.434
PET117	0.433
NDUFB9	0.432
NDUFAF3	0.432
PDSS1	0.432
TIMMDC1	0.429
NDUFA11	0.427
MRPS33	0.426
LRPPRC	0.426
MRPS2	0.421
PITRM1	0.42
MTPAP	0.419
COX11	0.418
NDUFS1	0.417
COA5	0.417
C17orf89	0.417
MTIF3	0.415
ATP5E	0.414
MRPS28	0.414
ATP5C1	0.414
AASDHPPT	0.413
TRIAP1	0.412
IBA57	0.412
TOMM6	0.412
COQ4	0.411
COA3	0.41
GATC	0.41
TOMM22	0.409
COX6C	0.408
NDUFB5	0.407
ELAC2	0.406
ATP5B	0.404
MRPL52	0.404
HCCS	0.403
MRPL12	0.402
RPUSD3	0.402
TOMM20	0.402
SSBP1	0.402
DHRSX	0.401
CARS2	0.401
TOMM7	0.4
GRSF1	0.4
CHCHD1	0.4

Global Fraction of Cell Lines Where Essential: 347/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	1/1
bile duct	10/28
blood	15/28
bone	13/26
breast	18/33
central nervous system	20/56
cervix	4/4
colorectal	11/17
esophagus	10/13
fibroblast	0/1
gastric	10/16
kidney	7/21
liver	10/20
lung	33/75
lymphocyte	9/16
ovary	7/26
pancreas	9/24
peripheral nervous system	8/16
plasma cell	3/15
prostate	0/1
skin	14/24
soft tissue	2/9
thyroid	1/2
upper aerodigestive	13/22
urinary tract	15/29
uterus	2/5

Essentiality in NALM6

Essentiality Rank: 1758
Expression level (log2 read counts): 5.79

Expression Distribution