RRP7A

Gene Information

Official Symbol: RRP7A
Official Name: ribosomal RNA processing 7 homolog A
Aliases and Previous Symbols: N/A
Entrez ID: 27341
UniProt: Q9Y3A4
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
DABN 20μM R00 exp17	-2.21
MLN-4924 2μM R00 exp22	-2.15
NFN1 0.1μM R01 exp49	1.71
Nifuroxazide 1μM R01 exp51	1.72
Cadmium 60μM R08 exp462	1.73
A-395N 10μM R05 exp219	1.77
Nicotinamide 2000μM R01 exp50	2.11
BH1 1μM R04 exp169	2.17
UM0011500 5μM R05 exp245	2.18

Gene	Correlation
TCEB3C	0.612
TCEB3CL	0.594
TCEB3CL2	0.592
PSMB2	0.585
POLR2J3	0.584
PSMB4	0.564
TBC1D3H	0.556
PSMA6	0.538
RPL35	0.534
CCNA2	0.529
PSMD2	0.523
TBC1D3G	0.521
TBC1D3F	0.513
POLA1	0.512
CHD4	0.511
AATF	0.511
C1QTNF9B	0.507
COX7A2L	0.506
EIF4A3	0.506
COPG1	0.504
NPIPB5	0.502
GOLGA6L3	0.501
ATP6V1A	0.499
SH3BP1	0.499
SLC6A17	0.498
COL2A1	0.497
VPS28	0.495
RPS2	0.495
UPF1	0.494
SLC38A7	0.494
C14orf93	0.493
SLC4A1	0.493
CDC45	0.492
UTP3	0.49
SUPT5H	0.49
POLR2D	0.49
TSG101	0.49
AQR	0.487
DTL	0.484
RPS5	0.482
CBWD3	0.482
TYMS	0.482
IK	0.481
INCENP	0.48
TBC1D3C	0.479
EXOSC6	0.478
PSMD14	0.478
TBC1D3	0.477
EBNA1BP2	0.476
NUP160	0.475
RPS12	0.475
PSMC2	0.474
NUP98	0.473
GOLGA6L4	0.473
LAD1	0.472
CBWD5	0.472
RPS19	0.472
POLE	0.471
TSPY8	0.467
TSPY1	0.467
KRT2	0.467
RPS10	0.466
ATP6V0C	0.466
BYSL	0.465
RUVBL2	0.465
VASN	0.465
TBC1D3E	0.462
TBC1D3L	0.462
FAM25B	0.462
TBC1D3K	0.461
LRR1	0.461
TBC1D3I	0.461
TIMELESS	0.461
HIST2H3A	0.46
HIST2H3C	0.459
KRT78	0.458
ACSF2	0.458
TUBA8	0.457
TSPY2	0.457
BRD2	0.457
INTS5	0.457
MTCH2	0.456
ORC1	0.456
RPL9	0.455
CHAF1A	0.454
WDR75	0.453
GOLGA8J	0.452
EXOSC9	0.452
POLR2L	0.452
POLR2A	0.45
KPNB1	0.45
ATP6V0B	0.449
ATP6V1B2	0.448
DDTL	0.448
MPP3	0.446
NFATC4	0.446
KCTD17	0.446
PSMB1	0.446
HIVEP3	0.443
PIGS	0.443
CTAGE4	0.443
UTP20	0.442
ATP6V1C1	0.441
RAD51	0.44
RPS19BP1	0.44
RPS7	0.44
PSMC6	0.438
XAB2	0.438
TWISTNB	0.436
FAM231C	0.435
FAM231A	0.435
RRP12	0.434
TINF2	0.434
PAN2	0.434
CACTIN	0.434
KIF3C	0.433
AKT1S1	0.433
PWP2	0.433
TONSL	0.433
WDR43	0.432
CBWD6	0.432
SNIP1	0.432
TP53TG3D	0.432
PRIM1	0.431
CLN6	0.429
PSMD7	0.428
SKIV2L2	0.428
UQCRH	0.428
ZDHHC19	0.428
RIOK2	0.427
RNPC3	0.427
SNRPA1	0.426
PDE4DIP	0.426
LIPE	0.426
CEP192	0.426
AAMP	0.425
PLRG1	0.424
NELFCD	0.424
RANBP2	0.424
PSMC4	0.423
TICRR	0.423
C3orf17	0.422
FCN2	0.422
ANKLE1	0.421
PSMA7	0.421
PAF1	0.421
CDC6	0.421
RPL6	0.42
SPATS2	0.42
SCGB1C1	0.42
TTC1	0.419
TPX2	0.418
ART5	0.418
MT1E	0.418
MMS22L	0.417
COPE	0.417
TMEM199	0.417
AHCTF1	0.417
PSMD6	0.416
DISP2	0.416
POLR1A	0.415
SF3A1	0.415
GOLGA6L6	0.415
GOLGA8O	0.413
POLR2F	0.413
NOC4L	0.413
RRN3	0.412
CHCHD3	0.411
NARFL	0.411
DDX18	0.411
C2orf27B	0.411
NPIPA7	0.41
COPB2	0.41
DHX38	0.41
GOLGA8K	0.41
TFIP11	0.41
ISY1	0.409
NPIPA8	0.409
EFTUD2	0.409
MCOLN1	0.409
NCL	0.408
DOCK6	0.407
NGDN	0.407
MED17	0.407
TRAPPC11	0.407
CHMP4B	0.407
PNO1	0.407
APC2	0.406
CCDC116	0.406
RNF113A	0.406
PSAP	0.406
FBL	0.405
TTYH1	0.405
EXOSC8	0.404
ANKLE2	0.404
SEC13	0.404
SART1	0.404
DNTTIP2	0.403
ISCU	0.403
CDCA3	0.402
ATP13A1	0.402
DIMT1	0.402
SSH2	0.402
EGR2	0.401
OSBP	0.401
MUL1	0.401
PRPF19	0.401
TRAIP	0.401
KRT5	0.4
ORC6	0.4

Global Fraction of Cell Lines Where Essential: 132/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	2/28
blood	2/28
bone	5/26
breast	7/33
central nervous system	9/56
cervix	0/4
colorectal	3/17
esophagus	2/13
fibroblast	0/1
gastric	3/16
kidney	3/21
liver	1/20
lung	20/75
lymphocyte	3/16
ovary	8/26
pancreas	3/24
peripheral nervous system	4/16
plasma cell	3/15
prostate	0/1
skin	4/24
soft tissue	0/9
thyroid	1/2
upper aerodigestive	3/22
urinary tract	5/29
uterus	1/5

Essentiality in NALM6

Essentiality Rank: 1172
Expression level (log2 read counts): 7.37

Expression Distribution