PCF11

Gene Information
  • Official Symbol: PCF11
  • Official Name: PCF11 cleavage and polyadenylation factor subunit
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 51585
  • UniProt: O94913
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene binds to CLP1 to form pre-mRNA cleavage factor IIm. The encoded protein is necessary for efficient Pol II transcription termination and may be involved in degradation of the 3' product of polyA site cleavage. [provided by RefSeq, Oct 2016].
  • UniProt Summary: Component of pre-mRNA cleavage complex II.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 706
  • Expression level (log2 read counts): 7.43

Expression Distribution

  • Last modified: 2025/12/10 20:19
  • by 127.0.0.1