MRPS24
Gene Information
- Official Symbol: MRPS24
- Official Name: mitochondrial ribosomal protein S24
- Aliases and Previous Symbols: N/A
- Entrez ID: 64951
- UniProt: Q96EL2
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: N/A
- UniProt Summary: N/A
Pfam Domains GO Terms
Pfam Domains
No Pfam Domain information is available for this gene.
GO Terms
| mitochondrial small ribosomal subunit |
| mitochondrial translational elongation |
| mitochondrial translational termination |
| translational termination |
| mitochondrial translation |
| translational elongation |
| cellular protein complex disassembly |
| mitochondrial gene expression |
| structural constituent of ribosome |
| protein-containing complex disassembly |
| translation |
| mitochondrial inner membrane |
| cellular component disassembly |
| peptide biosynthetic process |
| amide biosynthetic process |
| peptide metabolic process |
| cellular amide metabolic process |
| RNA binding |
| organonitrogen compound biosynthetic process |
| cellular nitrogen compound biosynthetic process |
| cellular macromolecule biosynthetic process |
| macromolecule biosynthetic process |
| protein-containing complex subunit organization |
| gene expression |
CRISPR Data
Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Compound Hit
| Screen | Score |
|---|---|
| GSK-J4 1.5μM R08 exp441 | 1.73 |
| Mitomycin-C 0.06μM R08 exp503 | 1.76 |
| Nocodazole 0.1μM R03 exp94 | 1.76 |
| Vinblastine 0.015μM R05 exp208 | 1.84 |
| Thimerosal 0.85μM R08 exp529 | 2.07 |
| iCRT14 30μM R08 exp492 | 2.22 |
Most Correlated Genes in Chemogenomics
| Gene | Correlation |
|---|---|
| MRPL53 | 0.635 |
| HSD17B10 | 0.62 |
| SELRC1 | 0.61 |
| YARS2 | 0.608 |
| MRPS34 | 0.608 |
| VARS2 | 0.604 |
| TARS2 | 0.602 |
| EARS2 | 0.6 |
| RPUSD4 | 0.599 |
| MRPS16 | 0.584 |
| MRPL23 | 0.584 |
| MRP63 | 0.575 |
| COX16 | 0.574 |
| MRPL21 | 0.573 |
| MRPS5 | 0.571 |
| FASTKD5 | 0.57 |
| SARS2 | 0.57 |
| MRPS26 | 0.564 |
| MRPS21 | 0.562 |
| PARS2 | 0.561 |
| MRPL47 | 0.559 |
| MRPS18A | 0.559 |
| NDUFA3 | 0.55 |
| MRPS2 | 0.548 |
| SCO2 | 0.548 |
| DAP3 | 0.547 |
| DARS2 | 0.544 |
| MRPS25 | 0.543 |
| KIAA0391 | 0.543 |
| LARS2 | 0.542 |
| NARS2 | 0.541 |
| MTERFD2 | 0.538 |
| MRPS6 | 0.536 |
| COX7B | 0.534 |
| GFM1 | 0.534 |
| SUPV3L1 | 0.528 |
| MTG2 | 0.527 |
| MARS2 | 0.525 |
| FTSJ2 | 0.525 |
| MRPS12 | 0.524 |
| C12orf65 | 0.524 |
| RNASEH1 | 0.524 |
| COA3 | 0.523 |
| NDUFAF7 | 0.522 |
| TEFM | 0.521 |
| MRPL12 | 0.519 |
| QRSL1 | 0.518 |
| AARS2 | 0.518 |
| FARS2 | 0.516 |
| UQCR10 | 0.516 |
| MRPS10 | 0.515 |
| HARS2 | 0.514 |
| BCS1L | 0.514 |
| MRPL55 | 0.512 |
| MTRF1L | 0.51 |
| MRPS9 | 0.509 |
| GATC | 0.509 |
| COA6 | 0.508 |
| NDUFB11 | 0.508 |
| MRPL15 | 0.505 |
| GTPBP10 | 0.503 |
| TUFM | 0.502 |
| MRPL20 | 0.502 |
| GFM2 | 0.501 |
| PET117 | 0.496 |
| RBFA | 0.495 |
| MRPL34 | 0.493 |
| MTPAP | 0.492 |
| RARS2 | 0.489 |
| MRPL44 | 0.489 |
| METTL17 | 0.488 |
| MTIF3 | 0.485 |
| COX6C | 0.483 |
| MRPS14 | 0.483 |
| TRUB2 | 0.479 |
| COX11 | 0.474 |
| MRPS17 | 0.473 |
| CHCHD4 | 0.472 |
| WBSCR16 | 0.471 |
| DHRSX | 0.471 |
| PET112 | 0.471 |
| PNPT1 | 0.469 |
| MRPL18 | 0.468 |
| C10orf2 | 0.468 |
| LRPPRC | 0.464 |
| PDSS1 | 0.464 |
| MRPS23 | 0.464 |
| MRPL17 | 0.463 |
| C17orf89 | 0.463 |
| MRPS35 | 0.462 |
| MRPL32 | 0.461 |
| POLG2 | 0.461 |
| COQ2 | 0.46 |
| MRPS33 | 0.459 |
| COQ3 | 0.457 |
| NDUFA2 | 0.455 |
| MRPL45 | 0.455 |
| MRPL46 | 0.455 |
| MRPL4 | 0.452 |
| MRPL43 | 0.451 |
| MRPL3 | 0.449 |
| MRPS7 | 0.448 |
| UQCRC2 | 0.446 |
| COX17 | 0.445 |
| MRPL37 | 0.441 |
| NDUFS2 | 0.44 |
| CARS2 | 0.439 |
| MTG1 | 0.439 |
| MRPL38 | 0.437 |
| CHCHD1 | 0.436 |
| NDUFB1 | 0.434 |
| MRPL11 | 0.434 |
| ALG8 | 0.433 |
| POLG | 0.432 |
| MIPEP | 0.432 |
| NDUFAF3 | 0.431 |
| NDUFS7 | 0.431 |
| NDUFV1 | 0.429 |
| TBRG4 | 0.428 |
| MRPL2 | 0.427 |
| RNMTL1 | 0.427 |
| MRPS11 | 0.426 |
| AIFM1 | 0.426 |
| ALAS1 | 0.423 |
| TOMM20 | 0.421 |
| MALSU1 | 0.421 |
| MRPL39 | 0.421 |
| PET100 | 0.42 |
| COX15 | 0.42 |
| MRPL41 | 0.419 |
| MRPL9 | 0.419 |
| COX6B1 | 0.419 |
| TOMM40 | 0.414 |
| MRPL42 | 0.414 |
| RPUSD3 | 0.413 |
| COQ6 | 0.411 |
| TFAM | 0.41 |
| NDUFC2 | 0.408 |
| MINOS1 | 0.406 |
| RPIA | 0.405 |
| MRPL33 | 0.405 |
| MRPS27 | 0.404 |
| COQ4 | 0.402 |
| SLC25A26 | 0.401 |
| ELAC2 | 0.401 |
| TOMM6 | 0.4 |
Tissues where Essential in the Avana Dataset (DepMap 20Q1)
Global Fraction of Cell Lines Where Essential: 113/739
| Tissue | Fraction Of Cell Lines Where Essential |
|---|---|
| 1290807.0 | 0/1 |
| 909776.0 | 0/1 |
| bile duct | 4/28 |
| blood | 4/28 |
| bone | 4/26 |
| breast | 5/33 |
| central nervous system | 4/56 |
| cervix | 2/4 |
| colorectal | 4/17 |
| esophagus | 4/13 |
| fibroblast | 0/1 |
| gastric | 3/16 |
| kidney | 4/21 |
| liver | 6/20 |
| lung | 12/75 |
| lymphocyte | 3/16 |
| ovary | 0/26 |
| pancreas | 1/24 |
| peripheral nervous system | 1/16 |
| plasma cell | 4/15 |
| prostate | 0/1 |
| skin | 4/24 |
| soft tissue | 2/9 |
| thyroid | 0/2 |
| upper aerodigestive | 5/22 |
| urinary tract | 6/29 |
| uterus | 1/5 |
Essentiality in NALM6
- Essentiality Rank: 1262
- Expression level (log2 read counts): 4.8
Expression Distribution
MRPS24 Expression in NALM6 Cells: 4.8
