TMEM242

Gene Information

Official Symbol: TMEM242
Official Name: transmembrane protein 242
Aliases and Previous Symbols: N/A
Entrez ID: 729515
UniProt: Q9NWH2
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Hypoxia 5%O2 R04 exp191	-1.99
SGC2043 10μM R03 exp152	-1.91
SGC0946 7μM R03 exp151	-1.86
VHL-ligand-1 20μM R07 exp421	-1.78
ONC212 0.15μM R08 exp513	1.7
Etoposide 0.3μM R05 exp199	1.73
Thimerosal 0.85μM R08 exp529	1.82
Doxorubicin 0.02μM R08 exp478	1.91
TIC10 10μM R08 exp532	1.91
Olaparib 4μM R08 exp512	1.93
Aphidicolin 0.4μM R08 exp440	2.05
Cannabidiol 13μM R08 exp465	2.07
42°C R08 exp539	2.09
Cannabidiol 20μM R08 exp466	2.15
Atovaquone 15μM R08 exp451	2.18

Gene	Correlation
MRPL21	0.601
SELRC1	0.594
ATP5D	0.572
BCS1L	0.572
YARS2	0.572
ATP5B	0.568
EARS2	0.564
ATP5A1	0.561
ATP5C1	0.56
C17orf89	0.557
FH	0.554
FASTKD5	0.553
MRPS5	0.551
MRPS34	0.551
SUPV3L1	0.549
RNASEH1	0.549
LSM10	0.546
GATC	0.542
DNLZ	0.542
HSD17B10	0.538
SCO2	0.537
NARS2	0.536
COX16	0.531
TARS2	0.529
RPUSD4	0.527
DAP3	0.525
NDUFB5	0.525
SLC25A26	0.522
MRPL23	0.517
THG1L	0.512
ATP5O	0.509
GFM2	0.505
MRPS14	0.504
VARS2	0.503
PGM3	0.502
GTPBP10	0.501
QRSL1	0.501
PARS2	0.501
TRMT61A	0.499
RPIA	0.498
PDSS1	0.496
MRPS16	0.493
MRP63	0.492
DHRSX	0.489
LARS2	0.486
MRPS2	0.485
C12orf65	0.484
MRPS18A	0.482
PPP6C	0.482
AASDHPPT	0.481
GFM1	0.481
TRIAP1	0.48
HARS2	0.48
RBFA	0.478
SARS2	0.477
ATP5H	0.477
KIAA0391	0.476
TEFM	0.475
MTG1	0.474
ATP5J	0.474
SLC25A19	0.472
MRPL47	0.471
PMM2	0.471
PMVK	0.47
DARS2	0.468
TEN1	0.468
POLG	0.466
MRPL12	0.465
GEMIN7	0.465
N6AMT1	0.464
MRPS6	0.462
MRPS21	0.461
MRPS26	0.46
TUFM	0.459
HCCS	0.457
NDUFA3	0.456
COX7B	0.455
MRPS10	0.453
OPA1	0.452
NDUFB11	0.452
MIPEP	0.452
MTG2	0.451
C10orf2	0.447
DOHH	0.446
COA6	0.445
ATPAF2	0.444
PET112	0.443
MRPL55	0.443
ALG1	0.443
PPCS	0.442
MRPL53	0.442
RARS2	0.442
CHCHD4	0.442
MRPS9	0.442
COQ3	0.441
UAP1	0.441
FARS2	0.44
TPK1	0.44
MTRF1L	0.439
AARS2	0.437
MRPL20	0.436
WBSCR16	0.436
ATP5L	0.435
WARS2	0.434
ZCRB1	0.431
COA3	0.427
PRKRIR	0.426
MRPL15	0.426
NDUFAF4	0.425
ATP5E	0.424
PPCDC	0.424
PET100	0.423
UQCR10	0.423
MARS2	0.422
POLG2	0.422
NDUFB6	0.422
SSB	0.421
ALDH18A1	0.421
MRPS25	0.42
NDUFV1	0.42
UQCC2	0.419
NDUFAF7	0.418
TRMT10A	0.418
ATXN10	0.416
PDCD5	0.416
MRPS11	0.415
FTSJ2	0.415
SLC25A3	0.415
ELAC2	0.415
TAMM41	0.414
PTPMT1	0.414
DHX30	0.414
ADSL	0.414
RPTOR	0.412
RPP21	0.412
VEZT	0.411
MTIF3	0.411
G6PD	0.411
ZRSR2	0.411
IBA57	0.41
COX11	0.407
ATP5SL	0.406
COX15	0.406
COX5A	0.405
GEMIN8	0.404
ECSIT	0.401
MBTPS2	0.4

Global Fraction of Cell Lines Where Essential: 1/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	0/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 6425
Expression level (log2 read counts): 3.87

Expression Distribution