PPA2

Gene Information
  • Official Symbol: PPA2
  • Official Name: inorganic pyrophosphatase 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 27068
  • UniProt: Q9H2U2
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: The protein encoded by this gene is localized to the mitochondrion, is highly similar to members of the inorganic pyrophosphatase (PPase) family, and contains the signature sequence essential for the catalytic activity of PPase. PPases catalyze the hydrolysis of pyrophosphate to inorganic phosphate, which is important for the phosphate metabolism of cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008].
  • UniProt Summary: N/A

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 1965
  • Expression level (log2 read counts): 5.73

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1