QRICH1

Gene Information

Official Symbol: QRICH1
Official Name: glutamine rich 1
Aliases and Previous Symbols: N/A
Entrez ID: 54870
UniProt: Q2TAL8
Interactions: BioGRID
PubMed articles: Open PubMed
OMIM: Open OMIM

Function Summary

Entrez Summary: N/A
UniProt Summary: N/A

Pfam Domains GO Terms

CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Screen	Score
Wortmannin 5μM R00 exp38	-4.35
Combretastatin A4 0.002 to 0.003μM day4 R04 exp179	-3.84
Epothilone-B 0.0015μM R05 exp231	-3.73
BML-284 0.09μM R08 exp460	-3.54
Vincristine 0.0005μM R04 exp190	-3.22
Nutlin-3A 1.6μM R06 exp294	-3.16
Lead acetate 2000μM R08 exp498 no dilution day6	-3.12
Docosahexaenoic-acid 50μM R07 exp356	-3.05
Colchicine 0.009μM R05 exp215	-3.03
Demecolcine 0.03μM R05 exp228	-3.02
Pimelic-diphenylamide-106 0.5μM R00 exp27	-2.95
GSK626616 14μM R08 exp485	-2.93
Ixabepilone 0.004 to 0.005μM on day4 R04 exp184	-2.91
Mdivi-1 15μM R05 exp217	-2.89
Thapsigargin 0.005μM R07 exp407	-2.86
Vinblastine 0.002μM R01 exp60	-2.86
RO-3306 3 to 4μM on day4 R04 exp165	-2.8
Ibrutinib 10μM R08 exp442	-2.76
Amiloride 100μM R08 exp447	-2.72
NN-Diethyl-meta-toluamide 100μM R05 exp237	-2.72
HMS-I2 10μM R06 exp288	-2.72
NN-Diethyl-meta-toluamide 500μM R08 exp438	-2.69
Chloramphenicol 2μM R00 exp12	-2.68
Diepoxybutane 3μM R07 exp354	-2.57
Centrinone 0.5μM R07 exp343	-2.56
35°C R06 exp302	-2.55
VER-155008 3.9μM R06 exp301	-2.53
Dexamethasone 0.006μM R07 exp351	-2.52
Senexin-A 25μM R07 exp400	-2.52
CR131-b 0.005μM R08 exp474	-2.51
HMS-I1 10μM R06 exp256	-2.51
Tenofovir 10μM R07 exp405	-2.5
∆-9-Tetrahydrocannabinol 30μM R08 exp445	-2.47
WNT3A 44ng/ml R08 exp537	-2.45
4-Nitroquinoline-1-oxide 0.5μM R08 exp446	-2.42
MK2206 4μM R08 exp504	-2.41
2-Methoxyestradiol 0.55 to 0.75μM on day4 R07 exp311	-2.4
Dynasore 7μM R08 exp436	-2.4
Etoposide 0.1μM R05 exp198	-2.38
SGC2096 2.6μM R03 exp153	-2.36
WYE-354 6μM R02 exp90	-2.36
Cabazitaxel 0.001μM R05 exp223	-2.35
UMK57 0.6μM R03 exp107	-2.35
Pimelic-diphenylamide-106 5μM R00 exp28	-2.33
Sulforaphane 9μM R08 exp525	-2.33
Methotrexate 0.01μM R08 exp501	-2.32
Wortmannin 0.5μM R00 exp37	-2.32
FK-506 30μM R07 exp359	-2.31
IU1-C 25μM R04 exp183	-2.3
Arsenate 40μM R06 exp264	-2.3
2-Methoxyestradiol 0.55 to 1μM on day4 R07 exp312	-2.27
Quercetin 20μM R08 exp517	-2.26
CAY10603 0.55μM R08 exp467	-2.25
UM0131023 0.05μM R05 exp248	-2.25
S-trityl-L-cysteine 0.5μM R05 exp243	-2.23
Heregulin-B 44ng/ml R08 exp486	-2.21
Apcin 50 to 100μM on day4 R04 exp176	-2.2
Sucrose 20000μM R06 exp298	-2.19
GSK-J4 1-1.25μM to day4 R07 exp363	-2.18
BAY-598 4μM R05 exp220	-2.17
CB-839 10μM R05 exp224	-2.17
UM131593 0.2μM R03 exp106	-2.17
BVD-523 15μM R02 exp67	-2.16
Dynasore 10μM R04 exp180	-2.15
I-BRD9 4μM R07 exp365	-2.14
Sulforaphane 9μM R08 exp526 no dilution day6	-2.14
Genistein 15μM R07 exp360	-2.13
LB-100 2μM R05 exp210	-2.12
MSC2530818 10μM R07 exp379	-2.12
Deguelin 0.15μM R05 exp209	-2.11
CoCl2 18μM R07 exp346	-2.1
Ribavirin 10 to 15μM on day4 R04 exp160	-2.1
Menadione 5μM R06 exp292	-2.09
Rapamycin 10μM R00 exp30	-2.08
Alpha-Amanitin 0.5μM R00 exp5	-2.07
B02 10μM R08 exp453	-2.07
BH1 1μM R04 exp169	-2.07
2-Methoxyestradiol 0.55μM R07 exp310	-2.06
MLN-4924 0.2μM R00 exp21	-2.04
Cannabidiol 20μM R08 exp466	-2.03
Epothilone-D 0.004 to 0.006μM on day4 R05 exp232	-2.03
PFI-2 4μM R05 exp239	-2.02
UM0011500 5μM R05 exp245	-2.02
Lead acetate 2000μM R08 exp497	-2.01
Tunicamycin 0.04μM R07 exp418	-2
Rapamycin 1μM R00 exp29	-1.99
Tunicamycin 0.04 to 0.125μM on day4 R07 exp420	-1.99
Taxol 0.004μM R03 exp103	-1.96
UMK57 1μM R01 exp59	-1.95
Nifuroxazide 5μM R03 exp102	-1.94
Vinorelbine 0.001μM R05 exp249	-1.9
DKK1 89ng/ml R08 exp477	-1.88
Rotenone 20μM R00 exp34	-1.88
CI-1040 9.5μM R08 exp472	-1.87
Bortezomib 0.005μM R00 exp6	-1.84
SB202190 10μM R03 exp148	-1.81
Rifampicin 10μM R00 exp32	-1.79
Cadmium 60μM R08 exp462	-1.74
Ibrutinib 1μM R07 exp372	-1.74
Dimethyl-Sulfoxide 1pc R03 exp120	-1.73
GSK-J4 1.5μM R08 exp441	-1.73
TNF-alpha 44ng/ml R08 exp533	-1.72
LB-100 4.1μM R02 exp72	-1.71
Fluvastatin 2.2μM R06 exp282	1.81

Global Fraction of Cell Lines Where Essential: 3/739

Tissue	Fraction Of Cell Lines Where Essential
1290807.0	0/1
909776.0	0/1
bile duct	0/28
blood	1/28
bone	0/26
breast	0/33
central nervous system	0/56
cervix	0/4
colorectal	0/17
esophagus	0/13
fibroblast	0/1
gastric	0/16
kidney	0/21
liver	0/20
lung	0/75
lymphocyte	0/16
ovary	0/26
pancreas	0/24
peripheral nervous system	0/16
plasma cell	0/15
prostate	0/1
skin	0/24
soft tissue	0/9
thyroid	0/2
upper aerodigestive	0/22
urinary tract	0/29
uterus	0/5

Essentiality in NALM6

Essentiality Rank: 14833
Expression level (log2 read counts): 7.1

Expression Distribution

regulation of cell morphogenesis
molecular function
regulation of anatomical structure morphogenesis
DNA-binding transcription factor activity, RNA polymerase II-specific