SSH2

Gene Information
  • Official Symbol: SSH2
  • Official Name: slingshot protein phosphatase 2
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 85464
  • UniProt: Q76I76
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: N/A
  • UniProt Summary: Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. {ECO:0000269|PubMed:11832213}.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 2029
  • Expression level (log2 read counts): 7.08

Expression Distribution

  • Last modified: 2026/01/07 22:37
  • by 127.0.0.1