ALG6

Gene Information
  • Official Symbol: ALG6
  • Official Name: ALG6 alpha-1,3-glucosyltransferase
  • Aliases and Previous Symbols: N/A
  • Entrez ID: 29929
  • UniProt: Q9Y672
  • Interactions: BioGRID
  • PubMed articles: Open PubMed
  • OMIM: Open OMIM
Function Summary
  • Entrez Summary: This gene encodes a member of the ALG6/ALG8 glucosyltransferase family. The encoded protein catalyzes the addition of the first glucose residue to the growing lipid-linked oligosaccharide precursor of N-linked glycosylation. Mutations in this gene are associated with congenital disorders of glycosylation type Ic. [provided by RefSeq, Jul 2008].
  • UniProt Summary: Adds the first glucose residue to the lipid-linked oligosaccharide precursor for N-linked glycosylation. Transfers glucose from dolichyl phosphate glucose (Dol-P-Glc) onto the lipid-linked oligosaccharide Man(9)GlcNAc(2)-PP-Dol.

Pfam Domains GO Terms


CRISPR Data

Compound Hit Most Correlated Genes in Chemogenomics Tissues where Essential in the Avana Dataset (DepMap 20Q1)

Essentiality in NALM6
  • Essentiality Rank: 3614
  • Expression level (log2 read counts): 5.58

Expression Distribution

  • Last modified: 2026/01/07 22:36
  • by 127.0.0.1