RBM39
Gene Information
- Official Symbol: RBM39
- Official Name: RNA binding motif protein 39
- Aliases and Previous Symbols: N/A
- Entrez ID: 9584
- UniProt: Q14498
- Interactions: BioGRID
- PubMed articles: Open PubMed
- OMIM: Open OMIM
Function Summary
- Entrez Summary: This gene encodes a member of the U2AF65 family of proteins. The encoded protein is found in the nucleus, where it co-localizes with core spliceosomal proteins. It has been shown to play a role in both steroid hormone receptor-mediated transcription and alternative splicing, and it is also a transcriptional coregulator of the viral oncoprotein v-Rel. Multiple transcript variants have been observed for this gene. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Aug 2011].
- UniProt Summary: Transcriptional coactivator for steroid nuclear receptors ESR1/ER-alpha and ESR2/ER-beta, and JUN/AP-1 (By similarity). May be involved in pre-mRNA splicing process. {ECO:0000250}.
CRISPR Data
Essentiality in NALM6
- Essentiality Rank: 680
- Expression level (log2 read counts): 8.67
RBM39 Expression in NALM6 Cells: 8.67
